Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"protein deposition"”.
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Protein deposition at polymer surfaces:the bulk and surface structure-property effects of hydrogels
… to investigate the interfacial phenomenon of protein adsorption in relation to the bulk and surface structure-property effect s of hydrogel polymers. In order to achieve this it was first necessary to characterise the bulk and surface properties of the hydrogels, with regard to the structural …
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Influence of dietary amino acid adequacy on performance and muscle protein turnover in poults
… to investigate changes in muscle composition and protein turnover in response to essential (EAA) and nonessential amino acid (NEAA) supplementation of the low protein diet. Developmental changes in muscle metabolism as well as differences between muscles were also examined. Protein synthesis was …
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Novel high water content hydrogels
… materials resulted that showed reduced protein deposition over the neutral core material. It is postulated that a sulphonate group would have a larger number of hydration shells around it than for example methacrylic acid, leading to more dynamic exchange and so reducing the adsorption …
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Acrylamide Based Hydrogels for Continuous Wear Contact Lenses
… having a reduced tendency for spoilation by protein deposition will be outlined, together with details of lens manufacture, toxicological testing, and wearing trials that have been carried out prior to the material becoming commercially available.
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Molecular investigations of gene families encoding foldase enzymes in wheat
The storage proteins of wheat (Triticum aestivum L.) form large polymers commonly referred to as gluten. These polymers are critical in determining important traits, especially in the processing qualities of dough. Vast amounts of research on the storage proteins and the genes encoding them have …
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Effects of varying energy intakes on mammary growth and development in prepubertal heifers
… 4 increasing grades were used to quantify ECM protein deposition. Lumenal and stromal areas were 3.5 ± 1.4% higher (p<0.01) and 4.0 ± 1.7% lower (p<0.01), respectively, in HH and HL heifers. Ki67 labeling in terminal ductular units and subtending ducts was 2.1 ± 0.8% (p<0.01) and 1.4 ± 0.7% …
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Muscle Growth and Development in Intrauterine Growth Restricted Pigs
… how intrauterine growth restriction alters protein deposition in skeletal muscle; 3) investigate whether branched-chain amino acids (BCAA) are able to enhance protein synthesis in intrauterine growth restricted (IUGR) pig muscle. Newborn piglets were considered normal body weight (NBWT) or …
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Controlling Tissue Matrix Assembly of Human Mesenchymal Stem Cells toward Engineering Native-like Bone, Cartilage, and Osteochondral Grafts
… by regulating nucleation, mineral-binding protein deposition sites, and affinity for mineral binding. Native-like articular cartilage with physiologic form and function was created using a cell pellet compression technique, a process mimicking the native developmental mesenchymal cell …
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Mitigating protein aggregation to reduce the toxicity inherent to Parkinson’s and Alzheimer’s diseases
Protein deposition in the form of amyloid fibrils is the hallmark of more than 40 human pathologies, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Misfolded protein oligomers formed as intermediates during the aggregation process have been strongly implicated in the onset and …
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Regulation of protein metabolism in skeletal muscle of low-birth-weight neonatal pigs
… attributed to rapid myonuclear accretion and protein deposition in muscle. Low-birth-weight (LBWT) neonates experience restricted muscle development, which leads to impaired postnatal growth and metabolic disorders later in life. The overall hypothesis of this dissertation was that dysfunction …
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Efficacy of guanidinoacetic acid supplementation to growing cattle and relative bioavailability of guanidinoacetic acid delivered ruminally or abomasally
… donor in a corn-based diet did not improve protein deposition in growing steers.
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Novel hydrogels for keratoprosthesis
… successfully incorporated in order to modulate protein deposition and cell adhesion. Porous peripheral skirts were fabricated using different types of porosigen. The water content mechanical properties, surface properties and cell response of these various materials have been investigated in …
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Micro/Nanoencapsulation of Proteins Within Alginate/Chitosan Matrix by Spray Drying
Currently, therapeutic proteins and peptides are delivered subcutaneously, as they are readily denatured in the acidic, protease rich environment of the stomach or gastrointestinal track and low bioavailability results from poor intestinal absorption through the paracellular route. Encapsulation of …
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Protein Misfolding and Aggregation in Neurodegeneration: In Vitro And In Vivo Study Cases
… and morbidity, intracellular and extracellular protein misfolding and accumulation appears as a common pathological pathway. In the present thesis work I analyzed two cases of toxic protein deposition involved in ALS and AD. First, I looked at SOD1-G93A mutant protein, whose neuronal deposit is …
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Cytochrome c-DNA and cytochrome c-enzyme interactions for the construction of analytical signal chains
… approaches, the redox properties of the protein cytochrome c (cyt c), which acts as an electron shuttle in the respiratory chain, was utilized to engineer ET chains on electrode surfaces. With the help of the biopolymer DNA, the redox protein assembles into electro active multilayer (ML) …
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INTERACTIVE EFFECT OF DIETARY FIBRE AND IMMUNE CHALLENGE ON THREONINE REQUIREMENT AND INTESTINAL BARRIER FUNCTION IN GROWING PIGS
… are thought to limit amino acid availability for protein deposition (PD) and growth in pigs. Fibre and threonine (Thr) may also play an important role in intestinal barrier function. Therefore, this thesis evaluated the independent and combined effects of high DF and immune challenge [Salmonella …
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S-Schichtproteine als molekulare Bausteine zur Funktionalisierung mikroelektronischer Sensorstrukturen
Bakterielle Zellhüllenproteine (S-Schichten) können als molekulare Bausteine zur Funktionalisierung technischer Oberflächen verwendet werden. Die Proteine fungieren dabei als formgebende Muster (Template) oder vermitteln Bindungsstellen für eine nanostrukturierte Materialsynthese. In der …
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Comparative study of the subcellular localisation and the N-glycosylation patterns of a recombinant glycoprotein expressed in Oryza sativa, Nicotina tabacum and Medicago truncatula
… of biologically active complex recombinant proteins. So far, research has been focussed on increasing accumulation levels of recombinant proteins expressed in many plant models. On the other hand, the cell compartment where recombinant proteins are deposited often refers to protein quality …
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Limiting amino acids for growing cattle fed diets based on corn and corn gluten feed
Ruminants rely on microbial protein as a significant source of amino acids (AA), yet ambitious production goals may increase AA requirements beyond supplies of AA provided by microbial protein. Providing growing cattle with adequate quantities of post-ruminal, absorbable AA is essential for …
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