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Showing 1 to 7 of 7 for “"protein classification"”.
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Protein Classification and Natural Kinds
… the record straight regarding which parts of protein classification are pluralist. Assuming an approach that attempts to draw metaphysical conclusions by analyzing how multifaceted practices of science work, I tie the results of my survey of protein classification practices to the debate over …
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Studies on Combining Sequence and Structure for Protein Classification
… is to develop a better understanding of how proteins evolve different structures and functions. A large scale protein clustering can provide a useful platform to identify such principles of protein evolution. Manual classification schemes accurately group homologous proteins, but they are …
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Predicting Flavonoid UGT Regioselectivity with Graphical Residue Models and Machine Learning.
… to a challenging and biologically significant protein classification problem: the prediction of flavonoid UGT acceptor regioselectivity from primary protein sequence. Novel indices characterizing graphical models of protein residues are introduced. The indices are compared with existing amino …
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Exploring Sequence-Structure-Function Relationships in Proteins Using Classification Schemes
With the rapid growth in the number of available protein sequences and structures, the necessity of interpreting this data in comprehensive and meaningful ways becomes increasingly apparent. Identifying and categorizing the functional, structural, and evolutionary relationships between proteins is …
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Community Classification of the Protein Universe
Protein family databases are an important resource for biologists seeking to characterise the function of proteins, the structure of their domains, and their localisation within the cell. Operating a protein family database requires the identification of families, and the curation of literature …
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Characterisation of two desiccation-linked dehydrins from Xerophyta humilis
… to express Late Embryogenesis Abundant (LEA) proteins as protective mechanisms. However, despite two decades of research, little is understood about their physiological functions and this has led to extensive nomenclature, with a large amount of redundancy. The primary reason for this lack of …
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Computational discovery and modelling of tandem domain repeats in proteins
Domains are functional and evolutionary units of proteins that typically fold into stable globular structures. A small subset of natural multidomain proteins contain large arrays of nearly identical domains repeated in tandem, challenging some of our assumptions about protein folding and evolution. …