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Showing 1 to 1 of 1 for “"proteases; peptidomimetics; calpain; ring closing; metathesis; conformational constraint"”.
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Design and synthesis and testing of conformationally constrained peptidomimetics.
… describes the design, synthesis and testing of peptidomimetics pre-organised into bioactive conformations. Chapter One introduces the concept of peptidomimetics, their importance as potential pharmaceuticals. The concept of constraining a compound into a bioactive conformation (α-helix, β-turn …