Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"protease activation"”.
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Protease Activation and Inflammation in Acute Pancreatitis
… disease with high mortality and morbidity. Activation of pancreatic proteases, the inflammatory response and impaired pancreatic circulation are pathophysiological events that are important in order for the disease to develop. There is no specific treatment for severe AP, and no useful …
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Acute Pancreatitis. Studies on smoking and protease activation.
Background and aims: Activation of pancreatic proteases is considered to be a crucial event in the early phase of acute pancreatitis but the cause of this activation is not known. Most cases of acute pancreatitis can be attributed to either gallstone disease or alcohol abuse. However, little is …
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Visualizing Protease Activation, Retrochmp3 Activity, and VPR Recruitment During HIV-1 Assembly
… of my studies, I have determined when the HIV-1 protease becomes active during the assembly of new virions, elucidated the mechanism by which the protein retroCHMP3 has an antiviral function, and examined the kinetics of recruitment of the HIV-1 accessory protein Vpr. I have also added …
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Nanoparticle coatings for spatial and temporal control of cancer imaging and therapy
… of pro-domains that require cleavage for activation, and the formation of inhibitory and stimulatory networks that continually hold enzyme activity in balance. While nanomaterials have been developed with a myriad of functions for sensing or delivering biomolecules, the incorporation of …
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Genetic analysis of thymocyte apoptosis
… through a mechanism that requires transactivation and repression of gene transcription. Several targets of GR regulation have been identified, including Glutathione-S-Transferase M1 (GSTM1) and Nur77 expression, and NFB function, however no specific mechanism for activating GR-regulated …
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Nanosecond Pulsed Electric Field Effects on Cell Cycle and Apoptosis
… externalization at the plasma membrane, caspase protease activation, DNA fragmentation, release of cytochrome c from the mitochondrion, and membrane blebbing. An important regulatory protein in the apoptotic pathway is p53. The p53 protein functions to modulate the cell cycle by arresting cells …