Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"prostate cancer diagnosis"”.
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Radiolabeled Bombesin Analogs to Improve Prostate Cancer Diagnosis by PET Imaging
… G. Ce récepteur est fortement exprimé dans le cancer de la prostate, il est ainsi un biomarqueur potentiel pour ce cancer. La bombésine est un peptide de 14 acides aminés qui se lie avec une forte affinité au GRPR. Les analogues radio-marqués de la bombésine ont été utilisés intensivement pour …
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Towards a Reliable Deep Learning Framework for Prostate Cancer Diagnosis using Ultrasound
Reliable prostate cancer (PCa) detection using ultrasound is crucial for improving patient outcomes. Developing deep learning (DL) models for PCa detection is hindered by noisy labels and cancer heterogeneity. The purpose of this work is to develop a clinically applicable framework for DL-based …
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Diffusive Acoustic Confocal Imaging System (DACI): a novel method for prostate cancer diagnosis
… between healthy and the diseased tissues in the prostate. Speed of sound is chosen as the tool to quantify the alterations in the tissues’ mechanical properties at different pathological states. The current work presents a scanning configuration that features three components: an acoustic …
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Quality of Life After Prostate Cancer Diagnosis: A Longitudinal Prospective Cohort Study in Alberta, Canada
… First, we examined the associations of post-diagnosis physical activity and change in pre-diagnosis physical activity on quality of life (QoL) in prostate cancer survivors. Then, we identified post-prostate cancer diagnosis QoL trajectories over time in the population. METHODS: 830 prostate …
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Electrical Impedance Spectroscopy with Multi-modal Tissue Discrimination for Ultrasound-Guided Targeted Biopsy
Prostate cancer diagnosis has undergone considerable evolution in recent years. Men with significant lesions observed via magnetic resonance imaging (MRI) typically undergo targeted biopsy. In a prostate biopsy procedure, ultrasound (US) is used to place a biopsy needle in lesion(s) identified via …
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Germline HOXB13 G84E Mutation Inhibits MEIS1-HOXB13 Driven Tumor Suppression in Prostate Cancer
Prostate cancer (PrCa) continues to pose a burden to adult men in the United States, having the highest incidence and second highest mortality rates. A prostate cancer diagnosis in an immediate family member increases risk 2-3 fold. Standard of care treatment of PrCa targets the Androgen Receptor …
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Computational methods for cancer diagnosis and prognosis from FT-IR spectroscopy data
Prostate cancer (PCa) is the single most prevalent cancer in US men. PCa diagnosis and prognosis are crucial processes in managing patients and disease. These greatly affect decision-making of treatment and post-treatment strategies. Manual histologic assessment of stained tissue forms gold …
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The Experiences and Needs of Younger Couples Affected by Prostate Cancer: a Qualitative Study
Background: Prostate cancer (PCa) is often referred to as an illness affecting ‘older men, however the prevalence amongst younger men (aged ≤65) is rising. Illness- related stressors impact upon both members of the couple (man with PCa and partner/wife), and on their relationships, yet little is …
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The experiences of men receiving results of a prostate biopsy: a service evaluation
Cancer is a word that instils fear and uncertainty; therefore how a cancer diagnosis is communicated is paramount. This thesis is an evaluation of a service that enables men to telephone for the result of their prostate biopsy. The service has evolved over time initiated by patients need to know …
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Biochemical and Molecular Characterization of the Prostate-Specific Membrane Antigen (PSMA)
<p>Prostate cancer is the most common malignancy and the second leading cause of cancer death in males in the United States. Additionally, the number of deaths attributed to prostate cancer is increasing at a rate of approximately 8% a year. Development of new diagnostic and therapy strategies are …
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Cell-free DNA and tumor exosome cargo as diagnostic and prognostic marker for prostate cancer
According to the Global Cancer Statistics 2020, prostate cancer (PCa) is the second most commonly diagnosed male cancer and second leading cause of cancer death among men globally. Prostate cancer is known to be more aggressive among men of African origin with reasons not fully known. Previous …
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Evaluation of a stage II screening protocol for prostate cancer
In 2003, prostate cancer (PCa) is estimated to be the most commonly diagnosed cancer and third leading cause of cancer death in Canada. During PCa population screening, approximately 25% of patients with a normal digital rectal examination (DRE) and intermediate serum prostate specific antigen …
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Computational phase imaging for biomedical applications
… Traditionally, stained tissues are used in prostate cancer diagnosis instead. The reason is that tissue samples used in diagnosis are nearly transparent under bright field inspection if unstained. Contrast-enhanced microscopy techniques, e.g., phase contrast microscopy (PC) and differential …
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Exercise as medicine : reversing treatment toxicities in prostate cancer patients
A common treatment for prostate cancer, which is the most common form of cancer after skin cancer in Australian males, is androgen deprivation therapy (ADT). However, ADT is associated with an array of adverse effects including reduced bone and lean mass, loss of muscle strength, negative change in …
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Diagnostic and Prognostic Biomarkers for Early Prostate Cancer
Prostate cancer is diagnosed and treated primarily on the basis of histopathological assessment of biopsies and cancer extent. Unfortunately, this assessment, performed by pathologists on very small amounts of biopsy tissue, misrepresents patient’s true risk of having life-threatening cancer grade …