Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 667 for “"prostate cancer"”.
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Microrna Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development
… of cells with stem cell properties, called cancer stem cells (CSCs), which are believed to be responsible for tumor establishment, metastasis, and resistance to clinical therapy. It’s crucial to understand the regulatory mechanisms unique to CSCs, so that we may design CSC-specific …
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Nanotherapies for Treating Prostate Cancer
<p>Current prostate cancer treatment remains ineffective primarily due to ineffectual therapeutic strategies and numerous tumor-associated physiological barriers which hinder efficacy of anticancer agents. Therefore, the focus of this study was to investigate a new combination therapy approach for …
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Adaptive Radiation Therapy Of Prostate Cancer
… This retrospective study evaluated ART for prostate cancer treatment and radiobiological consequences. An IRB approved protocol has been used to evaluate actual dose delivery of patients with prostate cancer undergoing treatment with daily CBCT.</p> <p>The dose from CBCT was measured in …
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Prostate cancer recognition in ultrasound images
Our purpose is to aid medical doctors in prostate cancer detection via computer automated analysis of prostatic ultrasound imagery. Absorption of ultrasound signals is different in cancerous areas than in non-cancerous areas. The energy of the signal, the continuity of the signal, the …
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Molecular diagnosis in prostate cancer. PCA3.
Contains fulltext : 74427.pdf (Publisher’s version ) (Open Access)
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Role of Wnt5a in Prostate Cancer
… upregulated at both mRNA and protein levels in prostate cancer, but information regarding its role in predicting clinical outcome in patients after radical prostatectomy is limited. The aim of the present thesis is to define the role of Wnt5a protein expression in prostate cancer. We started by …
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Tomato Phytochemicals and Prostate Cancer Risk
… in tomato cell suspension cultures. DU 145 prostate tumor cells absorbed 14C-15- cis phytoene and an oxidized phytoene product and partially metabolized these compounds in vitro. To elucidate the biological roles of phytoene and phytofluene, it was essential to determine the biodistribution …
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Testosterone, Lycopene Isomers, and Prostate Cancer
… (NMU)-testosterone-induced prostate cancer in rats. Survival was analyzed to include only rats that died with adenocarcinomas of the accessory sex glands. Only tomato powder-fed (RR = 0.570; P = 0.009) rats experienced significantly increased survival as compared to placebo …
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Modeling recovery curves for prostate cancer
… for patients following 3 different forms of prostate cancer treatment. I propose a parametric model for those function level time series and show promise that the method can be applied to both simulated and real data.
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Chemosensory Evaluation of Prostate Cancer Cells
Prostate cancer is the most commonly diagnosed disease and second most commonly caused death among men in America. Although much controversy surrounds the current methods of detection, PSA test and biopsy, no new methods have been approved as an effective method of detection. Biomarkers and …
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Characterising the mechanism of DCUN1D1 activity in prostate cancer and identifying DCUN1D1 inhibitors for prostate cancer treatment
… in our lab demonstrated the role of DCUN1D1 in prostate cancer in vitro and in vivo. We also identified potential inhibitors of DCUN1D1 which inhibited the proliferation of prostate cancer cells in a DCUN1D1-specific manner. This study seeks to determine the mechanism of action of DCUN1D1 in …
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Characterising the mechanism of DCUN1D1 activity in prostate cancer and identifying DCUN1D1 inhibitors for prostate cancer treatment
… in our lab demonstrated the role of DCUN1D1 in prostate cancer in vitro and in vivo. We also identified potential inhibitors of DCUN1D1 which inhibited the proliferation of prostate cancer cells in a DCUN1D1-specific manner. This study seeks to determine the mechanism of action of DCUN1D1 in …
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Androgen Receptor and Prostate Cancer Cell Heterogeneity
… receptor (AR) plays an important role in prostate cancer (PCa) development and has been the main therapeutic target in advanced PCa. AR expression is heterogeneous in both primary PCa and castration resistant prostate cancer (CRPC). However, the functional significance of AR heterogeneity …
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The Epigenetics of Small Cell Prostate Cancer
<p>Small cell prostate cancer (SCPC) is an androgen receptor (AR) negative variant that can develop during the progression of castration-resistant AR-positive (AR<sup>+</sup>) prostate adenocarcinomas. While rare at initial diagnosis, SCPC is present in 10-20% of patients resulting in an aggressive …
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Range Adaptive Proton Therapy For Prostate Cancer
… to eliminate range uncertainty and enable prostate treatment with a single anterior beam by detecting the proton’s range at the prostate-rectal interface and adaptively adjusting the range in vivo and in real-time. Materials and Methods: A prototype device, consisting of an endorectal …
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THE ROLE OF POU5F1B IN PROSTATE CANCER
Accounting for 14% of all new cancer diagnosis in the United States, prostate cancer is the most commonly diagnosed cancer and the second leading cause of cancer related death in the United States. Prognosis for patients diagnosed with metastatic disease is especially poor, since no effective …
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Image analysis of prostate cancer tissue biomarkers
Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. However their use is still limited by …
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Biological activity of palmitoylcarnitine in prostate cancer
… in diabetes mellitus type II, obesity and kidney cancer. Certain dietary intervention studies have been shown to reduce serum and urinary levels of acylcarnitines. It was shown that palcar accumulates in prostate cancer tissue, possibly indicative of the metabolic changes associated with cancer …
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