Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"prostanoid receptors"”.
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Genetic Polymorphism of Prostanoid Receptors, CRTH2 and TBXA2R in Aspirin Hypersensitivity
… AIA and AIAU in an association with prostanoids receptor CRTH2 and TBXA2R. The human CRTH2 gene (official name GPR44) encodes a G protein-coupled chemoattractant receptor molecule which is expressed on Th2 cells including other allergy related cells like eosinophils, basophils and …
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The FP prostanoid receptor: Isoforms and functional studies
… number of species. Based on the cloning of other prostanoid receptors, we hypothesized that isoforms, or alternative splice variants of the FP receptor that differed in their functional coupling might exist. Using a corpus luteum library, we cloned a novel, truncated form of the FP prostanoid …
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Regulation of Endogenous Excitatory Neurotransmitters by Isoprostanes
… in the vitreous humor.|To investigate whether prostanoid production is involved in the inhibitory effect of 8-isoPGE2, eyeballs were pretreated with either flurbiprofen, a nonselective COX inhibitor; NS-398, a selective COX-2 inhibitor or furegrelate, a thromboxane (Tx) synthase inhibitor. All …
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Charakterisierung von Prostanoidrezeptoren an Podozyten der Maus
Prostaglandine sind an der Regulation wichtiger glomerulärer Funktionen beteiligt und spielen eine Rolle in der Pathogenese glomerulärer Erkrankungen. In der vorliegenden Arbeit sollte der Einfluss verschiedener Prostaglandine auf das Membranpotential, die Ionenleitfähigkeit, cAMP Akkumulation und …
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Cyclooxygenase-2 and prostaglandins in human endometrial function
… mediates its effects via four G protein coupled receptors namely EP1, EP2, EP3 and EP4. These receptors signal via alternate and sometimes opposing pathways. The initial aim of the research presented in this thesis was to investigate the temporal expression and signalling of the prostaglandin E2 …
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Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells
… level of COX enzymes and prostaglandin receptors in fibroids and autologous myometrium samples from women with fibroids. Real-Time reverse-transcriptase polymerase chain reaction (RT-PCR) revealed that the expression of COX enzymes, EP1, EP2 and EP4 prostanoid receptors and prolactin …