Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 97 for “"prostaglandins"”.
-
A synthesis of prostaglandins.
… general approaches to the chemical synthesis of prostaglandins are reviewed latterly concentrating upon the synthesis of the 'D' series. A total synthesis of the prostaglandin, PGD[1] methyl ester and epimers is presented this being developed using the following synthetic pathway. Alkylation of …
-
Cyclooxygenase-2 and prostaglandins in human endometrial function
A role for cyclooxygenase enzymes and prostaglandins (such as prostaglandin E2) has been observed in benign endometrial pathologies (endometriosis, excessive blood loss and dysmenorrhoea) and in adenocarcinoma. Cyclooxygenase and prostaglandin E synthase enzymes catalyse the conversion of …
-
An Analysis of Renin Control by Intrarenal Prostaglandins
Made available in DSpace on 2014-12-14T13:39:43Z (GMT). No. of bitstreams: 1 7811290.pdf: 6269580 bytes, checksum: 4d5e27e228173b9aaddbdbf573c7fbbb (MD5) Previous issue date: 1978
-
The role of prostaglandins in oxidant-induced pulmonary edema
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
-
The role of prostaglandins in spontaneous and induced labour
… in order to assess the clinical effects of prostaglandins and to evaluate their role in present modern day obstetrics. To this end pertinent clinical and laboratory studies were carried out. This has not been done before in the Republic of South Africa. It is considered that the following …
-
Role of Endogenous Prostaglandins on Kainic Acid Induced Seizure Activity
… of NSAID was due to the change of endogenous prostaglandins(PGs) and if so, what types are involved. This study was done to determine the effect of prostaglandins administered intra-cisternally on the KA-induced seizure activity aggravated by pre-treated or post-treated with COX-2 inhibitors. …
-
Chemical Methods for Studying the Biosynthesis of Lantibiotics and Prostaglandins
… into the first intermediate in the synthesis of prostaglandins via a radical mechanism. Prostaglandins play a number of roles in the body, including the regulation of blood flow to certain organs, controlling transport across membranes, and the stimulation of inflammation. A tyrosine radical is …
-
The Role(s) of Prostaglandins in The Reproductive Physiology of The Hen
Made available in DSpace on 2014-12-14T16:11:09Z (GMT). No. of bitstreams: 1 7624065.pdf: 2914966 bytes, checksum: a7e6f8e25d38f013afbfd50902a199fd (MD5) Previous issue date: 1976
-
Dietary fatty acids, prostaglandins and infectious and endotoxin challenges in guinea pigs
Thesis: M.S., Massachusetts Institute of Technology, Department of Nutrition and Food Science, 1984
-
Synthetic studies on prostaglandins: "synthesis of a new thia-PGEI analog"
A PGE1 analog, namely (±)-trans-2-(6'-carbomethoxyhexyl)-3- (E-3"-thia-1 "-octene)-4-hydroxycyclopentanone 71, has been prepared for the first time. Towards the synthesis of this compound, several synthetic approaches aimed at the preparation of the required acetylenic and E-halovinylic sulfides as …
-
Inflammation, Phagocytosis and Effect of Flunixin Meglumine During Endotoxin-Induced Mastitis (Therapy, Prostaglandins)
The objectives were to determine the following in endotoxin-induced mastitis: (1) milk concentrations of thromboxane B(,2) (TXB(,2)) and prostaglandin F(,2(alpha)) (PGF(,2(alpha))); (2) the pharmacokinetics of flunixin meglumine in lactating cattle; (3) the clinical efficacy of the flunixin …
-
The molecular pathways mediating the role of cyclooxygenase enzymes and prostaglandins in cervical neoplasias
… carcinomas can be activated by seminal plasma prostaglandins. Prostaglandin concentration in seminal plasma is 10,000 times higher than that found at a site of inflammation, and prostaglandin E2 is the predominant type of prostaglandin detected in semen. In order to investigate the potential …
-
Prostaglandins Modulate the Uterine Response to Infectious Bacteria in Postpartum and Estrous Cyclic Ewes
… the in vivo and in vitro role(s) of P4 and prostaglandins in immune function(s) associated with uterine infections. In Exp. 1, postpartum ewes (d 0 = parturition) were supplemented with either OIL or P4 (beginning on d 10) or were SHAM or OVEX. Vena caval blood and lymphocytes were collected …
-
cis-Arenediols as versatile chiral synthons in the synthesis of prostaglandins, cyclitols, carbohydrates, and alkaloids
The oxidation of simple benzene derivatives by a mutant of Pseudomonas putida, called 39-D, produces cis-arenediols (1). The diols are enantiomerically pure and can be used as synthons for the preparation of a variety of interesting compounds because of their stereochemistry and the special array …
-
Arachidonic acid metabolism by early ovine embryos and the role of prostaglandins in one aspect of embryonic development
… (HHT). Experiment 2 was to determine whether prostaglandins have a role in embryo hatching from the zona pellucida. Ewes were superovulated and bred artificially, and embryos were collected on d 7 of pregnancy. Embryos were incubated with ethanol (control), indomethacin, PGE₂ or indomethacin …
-
Regulation of Antepartum Relaxin Release in the Pregnant Rat: Role of the Maternal Pituitary Gland, Luteinizing Hormone and Prostaglandins
The regulation of the antepartum elevation and decline of serum relaxin levels in the pregnant rat is poorly understood, but may be related to functional luteolysis (Endocrinology 107:671, 1980). Factors which served as a beginning for the investigation of the regulation of antepartum relaxin …
Page 1 of 5