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Showing 1 to 6 of 6 for “"prostaglandin E2 receptor"”.
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Targeting Prostaglandin E2 Receptor EP2 for Treatment of High-Risk Neuroblastoma
<p>Prostaglandin E2 (PGE2) is a predominant proinflammatory regulator that plays pivotal roles in regulating tumor cell proliferation, migration, and invasion. It fosters an inflammation-enriched microenvironment that facilitates angiogenesis and immune evasion. Neuroblastoma (NB) is a lethal …
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The Prostaglandin E2 Receptor Subtype 3E and its involvement in tauopathies
… pathway which play a key role in synthesising prostaglandin E2 (PGE2) from arachidonic acid. PGE2 has been implicated in preclinical stages of Alzheimer’s disease, where elevated levels of PGE2 in the cerebrospinal fluid can be found, as well as aberrant amyloid processing in experimental …
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Genetic Polymorphism Study of Prostaglandin E2 Receptor Subtype EP4 gene (PTGER4) in Aspirin - Intolerant Urticaria
… 약 어 = viii I. 서 론 = 1 Ⅱ. 재료 및 방법 = 4 A. 프로스타글란딘 E2 수용체(PTGER4)의 단일염기다형성 연관성 연구 = 4 1. 직접염기서열 분석을 이용한 프로스타글란딘 E2 수용체의 단일염기다형성의 조사 = 4 2. 연구 대상 및 표현형 = 5 3. 유전자형 분석 = 5 B. 프로스타글란딘 E2 수용체의 단일염기다형성의 기능적 연구 = 11 1. 세포배양 = 11 2. 역전사 중합효소연쇄반응(RT-PCR)을 이용한 다양한 세포주에서의 PTGER4 유전자의 발현 = 11 3. Promoter …
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The Impact of Preovulatory Estradiol on the Oviductal and Uterine Environments, and Profit per Pregnancy Associated with the Detection of Estrus
… were fixed and embedded for localization of prostaglandin E2 synthase (PTGES) and prostaglandin E2 receptor 2 (PTGER2) localization by immunofluorescence. There was no difference in immunoreactivity of PTGER2 protein; however, immunoreactivity of PTGES protein tended to be more intense in …
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Binding and Signaling Differences between Prostaglandin E1 and E2 Mediated by Prostaglandin E Subtype Receptors
Prostaglandin E1 (PGE1) and E2 (PGE2) are ligands for the prostaglandin E2 receptor (EP) family, which consists of four subtype receptors, designated as EP1, EP2, EP3 and EP4. Interestingly, PGE2 mediates inflammation whereas PGE1 acts as an anti-inflammatory factor. However, the molecular basis of …
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Identifizierung der für die Agonisten-induzierte Phosphorylierung und Internalisierung relevanten Serine und Threonine in der C-terminalen Domäne des humanen Prostaglandin E2 Rezeptors, Subtyp EP4
… Rezeptoren mit sieben Transmembrandomänen. Für Prostaglandin E2 (PGE2) wurden bisher vier verschiedene Rezeptorsubtypen (EP-R) identifiziert. Der EP1-R ist an ein Gq-Protein gekoppelt und seine Aktivierung führt zu einer Erhöhung des intrazellulären InsP3/Ca2+-Spiegels, während der EP3-R an …