Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 821 for “"promoters"”.
-
Investigation of Streptomyces promoters
… of developmentally regulated Strepcomyces promoters, to isolate such promoters, to develop a computer assisted analysis system whereby potential promoter sequences could be determined and to use this in the analysis of the cloned promoters. Initially the suitability of the Streptomyces …
-
Characterization of six Arabidopsis AROGENATE DEHYDRATASE promoters
… motifs were identified for all six ADT promoters, as well as corresponding transcription factors with similar expression profiles to each enzyme. Seven stable transgenic Arabidopsis lines were also generated using ADT promoter-eGFP/GUS constructs to test expression in all tissues during …
-
Developing synthetic, minimal promoters in Saccharomyces cerevisiae
Promoters enable synthetic biologists to manipulate protein expression at the DNA level. For this reason, promoters are essential for almost all applications aiming to engineer an organism. Unfortunately, promoters available for eukaryotic organisms are derived directly from the genome. Such …
-
GENOME-WIDE PROTEIN MOLECULAR ARCHITECTURE OF HUMAN PROMOTERS
… (TBP, TFIIB, Pol II), and nucleosomes at promoters. We propose a refined model of human promoters characterized by bidirectional transcription, where two distinct PICs initiate on opposing strands while sharing common upstream regulatory regions. Our findings revealed that different …
-
The regulation of premature termination at divergent promoters
… that desired transcripts are being expressed. Promoters transcribe divergently, producing low-abundant upstream antisense RNAs (uaRNAs) in addition to a stable downstream RNAs. Thus, a central question is what mechanisms are sense RNAs more stable compared to most transcription events. It is …
-
Regulation of transcription initiation at guanine + cytosine-rich promoters.
… initiation at guanine + cytosine-rich promoters.
-
Protein Regulators of Phosphoinositides as Promoters of Cancer Metastasis
<p>Metastasis, the spread of cancer cells from a primary tumor to a distal organ, represents the predominant cause of mortality in patients with solid tumors. However, the molecular mechanisms underpinning this multistep progression are poorly defined. Successful metastasis requires a cancer cell …
-
Transcriptional Regulation of Promoters Containing Different Estrogen Response Elements
The actions of estrogen are mediated through estrogen receptor alpha (ERalpha), and ER beta (ERbeta), which bind to estrogen response elements (EREs) present in target genes and activate transcription, In order to gain a better understanding of how individual EREs influence the ability of …
-
Analysis of tandemly and divergently oriented spinach chloroplast promoters
… of the ATP synthase (atpB) may contain multiple promoters. Ba131 deletion analyses have determined that 3 out of 4 of the previously observed spinach atpB $5\sp\prime$ ends represent transcription initiation sites and not processing sites. A previously undetected transcript situated one codon …
-
Intracellular and extracellular promoters of metastasis to different organs
Metastasis is the cause of the vast majority of cancer-related deaths, yet much remains unknown about this complex process, from how tumor cells complete the many steps of the metastatic cascade to how they can adapt to survive in multiple, vastly different secondary sites. I have therefore …
-
Developing a Social Enterprise: An Investigation of Promoters and Barriers
… and nature of social<br/>enterprise, the promoters and barriers to its development in a specific context of the<br/>remote and rural North of Scotland and to investigate the extent to which social<br/>enterprise was being considered for health and care service provision. Giddens’ …
-
Function of core promoters in differential gene regulation during embryogenesis
… The recently discovered diversity of core promoters and basal transcription factors suggests a regulatory role in differential gene expression. However, the direct contribution of the core promoter remains poorly understood. I investigated core promoters and their putative role in …
-
Investigation of XvSap promoters from the resurrection plant, Xerophyta viscosa
… in crop biotechnology, four shortened promoters, XvSap1D, E, F and G were generated by mutagenesis. The generated promoters had circa 50% reduction in size and contained the 5' proximal and 3' distal regions of the XvPsap1 promoter with the internal region removed. The shortened …
-
Aedes aegypti Heat Shock 70 Genes and their Inducible Promoters
… assays. Deletion analysis of AaHsp70-derived promoters yielded two ~1.5 kb genomic fragments that maintained robust heat inducibility in these systems. Aedes aegypti were transformed with AaHsp70-luciferase gene cassettes using the transposable element Mos1. AaHsp70-luciferase transcripts …
-
Identification of Factors Involved In Dna Methylation of Cpg-Island-Promoters
… About one-fourth of empirically defined human promoters are surrounded by or contain clustered repetitive elements. It was previously observed that a sharp transition of methylation occurs between highly methylated repetitive elements (SINE or LINE) and unmethylated CGI-promoters (e.g. P16, …
-
Expression from the parvovirus B19 promoters in non-permissive human cells
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
-
Architecture of Escherichia coli promoters that respond to reactive nitrogen species
… by NarL was then studied using semi-synthetic promoters. The hcp gene was found to be positively regulated by FNR and negatively regulated by NsrR. Contrary to previous reports, NarL and NarP were found to have little direct effect on expression of hcp, however, an indirect effect of NarL was …
-
CO2 absorption into concentrated carbonate solutions with promoters at elevated temperatures
… solution by using amine and amino acid promoters. We will conduct an initial screening study using a lab scale stirred tank reactor. Promoters which showed the most potential were tested on a bench scale, packed bed column to simulate real process conditions. Five different …
-
An in vitro transcription termination system to analyze spinach chloroplast promoters
To determine whether chloroplast RNA polymerase would accurately terminate transcription in vitro, the 3$\sp\prime$ end of the rbcL gene as well as various factor-independent transcription terminators from E. coli were fused to the spinach chloroplast rbcL promoter. Transcription of the rbcL …
Page 1 of 42