Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"promoter polymorphisms"”.
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Association between Chronic Hepatitis B Virus Infection and Interleukin-10, Tumor Necrosis Factor-α Gene Promoter Polymorphisms
… the association between HBV infection and polymorphisms of tumor necrosis factor-a (TNF-α) and interleukin-10 (IL-10) gene promoter. We studied 412 Korean patients with HBV infection (72 inactive carriers, 261 chronic hepatitis, 79 liver cirrhosis) and 204 healthy individuals who recovered …
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Promoter Polymorphisms of Cysteinyl Leukotriene Receptor 1 (CysLTR1) Influence the Effect of Leukotriene Modifier on Transcriptional Regulation of the CysLTR1 Gene Induced by IL-4
… genetic association study of CysLTR1 genetic polymorphisms were performed in 105 aspirin intolerant asthma (AIA) patients, 111 aspirin tolerant asthma (ATA) patients, and 125 normal healthy controls (NC) . Promoter activities according to the genetic polymorphism were examined by luciferase …
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Genetic Effect of ALOX15 Polymorphisms on Aspirin-Exacerbated Respiratory Disease
… healthy controls (NC) were enrolled. Three polymorphisms (-427G/A, -272C/A, -217G/C) in the promoter were genotyped by a primer extension method. The functional variabilities of the promoter polymorphisms were analyzed by luciferase reporter activity assay, electrophoretic mobility shift …
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THE ROLE OF THE IL4/13 PATHWAY IN THE GENETICS OF ASTHMA SEVERITY
… not been explored. We tested single nucleotide polymorphisms (SNPs) in the critical Th2 regulator GATA-binding protein 3 (GATA3) and other Th2 genes for association with baseline lung function, allergic symptoms, and health care utilization in non-Hispanic whites (n=437) and African-American …
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Assoziation zwischen vier Polymorphismen des menschlichen Transforming-Growth-Factor-beta1-Gens und der zeitlichen Progression der posthepatitischen Leberfibrose
… to elucidate possible relationships between four polymorphisms of the TGF-beta1 gene (-800G>A; -509C>T; Leu10Pro; Arg25Pro) and stage, histological activity grade and progression rate (METAVIR-score) of liver fibrosis. Methods: Three study groups, i.e. 48 patients with hepatic fibrosis (26 with …
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Significant Association of IL-18 Genetic Polymorphisms with Aspirin-Intolerant Urticaria in a Korean Population
… recruited from Ajou University Hospital. Two promoter polymorphisms of IL-18 gene at -607A>C and -137G>C were genotyped using a primer extension method. The functional effects of the genetic polymorphims of IL-18 were examined by luciferase reporter assay, electrophoretic mobility shift assay …
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Genetic Effect of MBL2 Polymorphisms in Patients with Diisocyanate-induced Occupational Asthma
… To demonstrate genetic association of MBL2 polymorphisms in DI-OA, 99 patients with DI-OA, 99 asymptomatic exposed controls (AEC) and 144 unexposed normal controls were enrolled. Three polymorphisms (-554 G>C, -431 A>C and -225 G>C) in the MBL2 promoter were genotyped by TaqMan allelic …
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A Study Of The Molecular Genetics Of Renal Cell Carcinoma In Man
… and Alanine 588 to Threonine respectively. These polymorphisms are found within the oxygen-dependent degradation domain (ODD) of the HIF-lα protein when transcribed which is important in the oxygen regulation of the protein via hydroxylation of the proline residue at position 564 (P564) by HIF-α- …
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Mechanisms of microbial-host interaction during asymptomatic bacteriuria
… host response, patients were genotyped for polymorphisms that have been linked to susceptibility to ABU and urine samples from the patients were screened for 31 immune markers. The genetic polymorphisms in the interferon regulatory factor 3 (IRF3) and Toll-like receptor 4 (TLR4) promoter had …