Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"promoter polymorphism"”.
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Korrelation von genetischen Polymorphismen mit dem Schweregrad der Intimahyperplasie nach Stentimplantation
… this job investigated the influence of the PAI-1 promoter polymorphism on the "late loss" (a quantitative surrogate of the instent-restenosis) on 300 patients, smokers as well as non-smokers. The 4G/5G promoter polymorphism determines up to 40% of the PAI-1 plasma mirror. Whereas both alleles bind …
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Significant Association of IL-18 Genetic Polymorphisms with Aspirin-Intolerant Urticaria in a Korean Population
… perform genetic association study of IL-18 gene polymorphism with AIU, 247 patients with aspirin-intolerant urticaria (AIU) and 196 normal healthy controls(NC) were recruited from Ajou University Hospital. Two promoter polymorphisms of IL-18 gene at -607A>C and -137G>C were genotyped using a …
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5-HT1A receptor expression : Studies in postmortem tissue and characterisation of a model system.
… synthesis of 5-HT. A common single nucleotide polymorphism in the promoter region of 5HT[1A] receptor C-1019G is also associated with depression and suicide. The nuclear DEAF-1 related (NUDR) protein represses the 5-HT[1A] promoter region hence regulating both 5-HT[1A] transcription and …
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Strukturelle und funktionelle Untersuchung der Promotorregionen der menschlichen PAX3-, PAX6- und PAX7-Gene: Bedeutung von Polymorphismen für schizophrene Erkrankungen
… der mit diesen Promotoren assoziierten Repeat-Polymorphismen auf die Expression dieser Gene untersucht. Schliesslich wurde die Relevanz für die psychischen Erkrankungen wie die Schizophrenie getestet.
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Molecular genetic mechanisms of eosinophil activation in aspirin-exacerbated respiratory disease : Genetic mechanisms of eosinophil activation
… association of IL5, IL5RA and P2RY12 genetic polymorphisms in the susceptibility to asthma and AERD in a Korean population. Materials and Methods: The two study groups, 310 adult asthmatics and 160 normal controls (NC), were enrolled at Ajou University Medical Center, Suwon, South Korea. IL5 …
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Epigenetická regulace genů HLA II. třídy a jejich role u autoimunitních onemocnění.
Abstrakt Úvod: Diabetes mellitus 1. typu (T1D) je multifaktoriální autoimunitní onemocnění, jehož incidence v Evropě neustále roste. Největší genetické riziko T1D je spojováno s geny HLA (lidské leukocytární antigeny) II. třídy. HLA II. třídy hrají klíčovou úlohu při regulaci imunitní odpovědi. …