Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"prokinetic"”.
-
Improvement of Gastroparesis Management By Addressing Challenges in Drug Metabolism: Studies with Metabolite Identification, Reaction Phenotyping and In Vitro Drug-Drug Interactions
… due to chronic abnormal gastric motility. Prokinetic agents such as domperidone and metoclopramide are the cornerstone in treatment of gastroparesis. Although these medications have been used for decades, essential information about their metabolism is not available. Lack of knowledge about …
-
The effects of bit chewing on gastric emptying and orocecal transit times in clinically normal horses
… time which can be life-threatening. Various prokinetic medications have been associated with varying side effects, questionable efficacy, and increased cost. Gum chewing as a form of sham feeding is used as a safe, effective, well-tolerated, and inexpensive way to ameliorate ileus following …
-
Ingestible Electronics for High Quality Gastric Neural Recordings
… rate, and measure the expected response to prokinetic therapeutics. Multi-day measurements were obtained using MiGUT in a freely moving pig, recording changes in the slow wave during different behaviors with no artifacts observed during ingestion or movement. This type of data could enable a …
-
Gastro-duodenal motility & nutrition in the critically ill.
… that the antibiotic, cefazolin, may have a prokinetic effect. Cefazolin, however, did not demonstrate similar prokinetic activity at a ‘low’ dose (50mg) in a critically ill cohort. The results of this study do not support the use of this agent, at this dose, as a prokinetic, in this …
-
Serum concentrations of lidocaine and its metabolites after prolonged infusion in healthy horses
… infusions (CRI) are the most commonly used prokinetic in equine practice for the treatment of post-operative ileus and are also increasingly being used in pain management, such as in cases of severe laminitis, and are often used for prolonged durations. To date only limited …
-
Gastrointestinal (GI) Motility is Unaltered by Feeding in Zebrafish
… posterior intestine. The effects of Cisapride, a prokinetic in humans, was examined and found to increase the contraction number, velocity, and interval. The effects of Niflumic Acid and DIDS were also examined, because anoctamin 1 (ANOl), a chloride-selective channel, has recently been identified …