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Showing 1 to 2 of 2 for “"prokaryotic defense"”.

  1. Towards in vivo editing of the human microbiome

    … to leveraging bacterial conjugation and the prokaryotic defense system CRISPR-Cas9, we employed bacteriophages for depleting native strains to empty the niche for an engineered version. Our work enables applications in engineering probiotic strains with augmented fitness and anti-pathogenesis …

    mit Repository record for Towards in vivo editing of the human microbiome (opens in a new tab)

  2. Investigating Genetic (IN)Compatibility Between Temperate Phages and CRISPR-CAS Systems in Staphylococcus Aureus

    <p>Prokaryotic organisms employ various mechanisms for defending against parasitism by viruses and other mobile genetic elements. One form of defense comprises the adaptive immune systems derived from clustered, regularly interspaced, short palindromic repeat (CRISPR) loci and CRISPR-associated …

    rockefeller Repository record for Investigating Genetic (IN)Compatibility Between Temperate Phages and CRISPR-CAS Systems in Staphylococcus Aureus (opens in a new tab)