Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 8 of 8 for “"prognostic stratification"”.

  1. GENOMIC AND EPIGENETIC APPROACHES IN THE CLINICAL AND PROGNOSTIC STRATIFICATION OF CHRONIC LYMPHOCYTIC LEUKEMIA

    … allowed the investigation of a potential prognostic significance associated with the biological markers identified. Genome-wide DNA profiling and FISH were used to perform a deletion-mapping analysis of 17p in a subset of 18 CLLs with TP53 deletion and in all the investigated cases, the …

    milano Repository record for GENOMIC AND EPIGENETIC APPROACHES IN THE CLINICAL AND PROGNOSTIC STRATIFICATION OF CHRONIC LYMPHOCYTIC LEUKEMIA (opens in a new tab)

  2. Individualising prognostic stratification in non-metastatic prostate cancer: the development, validation and clinical impact assessment of the Predict Prostate tool.

    … despite some tumours being relatively indolent. Prognostic stratification should therefore help inform management. However, models currently used in clinical practice have significant flaws. This thesis sets out the rationale for a new individualised prognostic model, describes the development …

    cambridge Repository record for Individualising prognostic stratification in non-metastatic prostate cancer: the development, validation and clinical impact assessment of the Predict Prostate tool. (opens in a new tab)

  3. Morphological classification of childhood medulloblastomas with β-catenin immunohistochemistry and mycn fluorescent in situ hybridization

    … between the ages of 0 and 9 years. The basic prognostic stratification that relies on clinical and histological findings alone has proven unsatisfactory as an outcome predictor. Distinct molecular genetic profiles have been described, with four molecular variants of medulloblastoma with …

    cape-town Repository record for Morphological classification of childhood medulloblastomas with β-catenin immunohistochemistry and mycn fluorescent in situ hybridization (opens in a new tab)

  4. Characterising DNA methylation in tissue and liquid samples from patients with renal tumours

    … analysis, may have a role in RCC diagnosis and prognostication, but are unlikely to be sufficient alone due to low recurrence rates and significant intra-tumoral heterogeneity (ITH), which limit detection. Changes in DNA methylation are abundant and often early events in tumorigenesis, which may …

    cambridge Repository record for Characterising DNA methylation in tissue and liquid samples from patients with renal tumours (opens in a new tab)

  5. Evaluation of biomarkers for the diagnosis, management and follow-up of women with gestational trophoblastic disease

    … decisions, treatment strategies, and risk stratification for women with molar pregnancy, GTN and GTD mimics. These complex cases confirmed the pivotal role of serum hCG and molecular genotyping in monitoring disease persistence, prognostic stratification, and clinical management Novel …

    cork Repository record for Evaluation of biomarkers for the diagnosis, management and follow-up of women with gestational trophoblastic disease (opens in a new tab)

  6. COPEPTIN AS A SURROGATE MARKER OF ARGININE VASOPRESSIN:CLINICAL DIAGNOSTIC AND PROGNOSTIC APPLICATIONS IN ENDOCRINE AND NON-ENDOCRINE DISEASES

    … diseases as well, and a diagnostic and prognostic role of copeptin has been reported in conditions like acute myocardial infarction, ischemic stroke, congestive heart failure, sepsis. The aim of this dissertation was to investigate usefulness of copeptin measurement, under baseline and …

    milano Repository record for COPEPTIN AS A SURROGATE MARKER OF ARGININE VASOPRESSIN:CLINICAL DIAGNOSTIC AND PROGNOSTIC APPLICATIONS IN ENDOCRINE AND NON-ENDOCRINE DISEASES (opens in a new tab)

  7. Longitudinal Clonal Lineage Dynamics and Functional Characterization of Pancreatic Cancer Chemo-Resistance and Metastasization

    <p>In recent years, technological advancements, such as next-generation sequencing and single-cell interrogation techniques, have enriched our understanding in tumor heterogeneity. By dissecting tumors and characterizing clonal lineages, we are better understanding the intricacies of tumor …

    uthsc Repository record for Longitudinal Clonal Lineage Dynamics and Functional Characterization of Pancreatic Cancer Chemo-Resistance and Metastasization (opens in a new tab)