Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 508 for “"progenitors"”.
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Identification of Epo-independent red cell progenitors : the E-cad+ progenitors
Erythrozyten zählen zu den am häufigsten vorkommenden terminal differenzierten Zelltypen des menschlichen Körpers. Durchschnittlich werden täglich ca. 2 x 1011 von ihnen im Körper eines erwachsenen Menschen produziert. Die reifen Erythrozyten entstehen aus multipotenten hämatopoetischen …
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Apoptosis in Haematopoietic progenitors
Introduction: Intracranial pressure (ICP) monitoring is a cornerstone of care for patients with severe traumatic brain injury (TBI). The primary goal of ICP treatment is to preserve brain oxygenation, and since brain oxygenation is usually not measured, the control of ICP is used as a surrogate …
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Extragalactic Novae and Their Progenitors
… is simply not known. There is evidence that the progenitors of some Type Ia supernovae (SNe Ia) may be RG-nova systems (e.g. SN PTF11kx), therefore it is important to understand the population of such systems. In this thesis, archival Hubble Space Telescope (HST) data are used to search for …
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Vasogenic bloodborne progenitors and diabetes
… to three distinct populations of vasoactive progenitors which contribute to adult (postnatal) angiogenesis in different ways. The circulating EPC can be identified via flow cytometry from peripheral blood mononuclear cells (PBMC5),<br/>and serves as a measure of angiogenic potential. Myeloid …
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Progenitors Related to Simple Groups
… simple groups. We have presented several progenitors such as 2^{*8}:Z_4 wr Z_2, 3^{*3}:_m L(2,7), 2^{*4}:[2:2^2], 2^{*11}:D_{11} and many more on which we've found the mathieu group M12 and 2*[M21:2^2] among their homomorphic images. We give the full monomial automorphism groups of …
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REPROGRAMMING LUNG FIBROBLASTS INTO LUNG PROGENITORS
… could possibly reprogram fibroblasts into lung progenitors. Co-expression of multiple transcription factors, each with unique functional roles, will likely be required for direct reprogramming. Hence, we will assess different combinations of lung lineage-specific transcription factors to …
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THE PROGENITORS OF TYPE IIP SUPERNOVAE
Mass-loss prior to core collapse is arguably the most important factor affecting the evolution of a massive star across the Hertzsprung-Russel (HR) diagram, making it the key to understanding what mass-range of stars produce supernova (SN), and how these explosions will appear. It is thought that …
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Observational Investigations of the Progenitors of Supernovae
… explosions, thus informing on thenature of the progenitors.
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Rejuvenation of CNS Progenitors via Partial Reprogramming
Adult stem cells become less efficient at maintaining tissue integrity and repairing tissue damage with age. Oligodendrocyte progenitor cells (OPCs) are the largest population of stem cells in the adult CNS and give rise to oligodendrocytes. OPCs play a critical role in myelin regeneration …
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Characterization of human myeloid progenitors and their differentiation
… though the surface expression of GFRs on these progenitors coincides with the supposed regulating functions of the corresponding GFs, it cannot always be predicted by the gene expression. More specific studies of the proposed CMP revealed that this is a heterogeneous population, composed of a …
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Capturing Photosynthetic Traits from the Progenitors of Wheat
… associated with linkage drag from the wild progenitors. The progenitor individuals had higher CO2 assimilation per ear than cultivated bread wheat, most likely driven by awn presence. These findings led to an investigation of how awn presence influences ear and flag leaf photosynthesis, and …
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Supernova Rates, Rise-Ttmes and their Relations to Progenitors
… towards a long delay time since the birth of the progenitors systems and argue for progenitor stars of initial low mass. We calculate a stretch-corrected rise-time since explosion to maximum brightness for different sets of SNe~Ia. We find that a fiducial 17 day quadratic rise is sufficient to …
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Finding fossil galaxy system progenitors using strong gravitational lensing
… member galaxies over cosmic time. While the progenitors to fossil systems have been predicted to exist in numerical simulations, little effort has gone into locating them until now. The discovery of fossil progenitors in the CASSOWARY catalog of strong gravitational lensing demonstrates that …
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Hematopoietic Stem Cells and Progenitors in Murine Autoimmune Arthritis
… emphasis on Hematopoietic Stem Cells: HSCs) and Progenitors, in a spontaneous murine autoimmune arthritis model. We found that these mice have a systemic increase in myeloid cells, which correlated with an increased frequency of granulocyte-monocyte progenitors relative to other committed …
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Identification, regulation and lineage tracing of embryonic olfactory progenitors
… adult OE and central nervous system (CNS) progenitors and lineage trace their progeny, our spatial and temporal understanding of embryonic OE neuroglial progenitors has been stalled by the paucity of identifiable genes able to distinguish individual candidate progenitors. In the developing …
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Enediynylacridans: design and synthesis of oxidase triggered diyl progenitors
In 1972, Bergman reported cycloaromatization via 1,4- benzenoid diradicals of enediyne systems. Since 1985, five enediyne fungal products with anticancer antibiotic activity have been structurally elucidated, namely, neocarzinostatin chromophore, the calicheamicins, the esperamicins, the …
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ADDUCINS AFFECT CORTICAL NEUROGENESIS BY REGULATING PROGENITORS¿ MORPHOLOGY AND FATE
… cells, classified as apical (APs) and basal progenitors (BPs). BPs are significantly enriched and highly proliferating in gyrencephalic species compared to lissencephalic, leading to an increased neuronal outcome and to cortical folding. BPs are a highly heterogeneous population: they can be …
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Investigating neuroectodermal transdifferentiation: How do CNS progenitors form Schwann cells?
… tracing studies demonstrated that adult CNS progenitors, oligodendrocyte progenitor cells (OPCs), can produce SCs in vivo. The mechanisms underlying this damage-induced plasticity of OPC fate choice remain incompletely understood. Therefore, in this thesis I sought to understand how changes …
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Formation and evolution of hypernova progenitors in massive binary systems
The massive stellar progenitor of a hypernova explosion and an associated gamma-ray burst must satisfy two primary constraints: (1) the outer layers of the stellar core must possess sufficient angular momentum to form a centrifugally supported torus about the collapsed central object (a Kerr black …
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