Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"prodigiosin"”.
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Substrate elucidation and mutasynthesis: Characterisation of the biosynthetic pathway of a tripyrrolic secondary metabolite, prodigiosin
… realm of secondary metabolites. The tripyrrole prodigiosin illustrates this perfectly with activities ranging from antimicrobial to immunosuppressive and anticancer. Microorganisms producing the red pigment prodigiosin were first isolated more than 150 years ago. Yet, its structure was only …
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New Pleiotropic Co-Regulators of Gas Vesicle and Secondary Metabolite Production in Serratia sp. ATCC39006
… antibiotic, 2‐methyl‐3‐pentyl‐6‐methoxyprodigiosin (prodigiosin; a prodiginine) and the β-lactam antibiotic, 1-carbapen-2-em-3-carboxylic acid (a carbapenem). The production and regulation of GV assembly is a complex process, which is part of a wider regulatory network affecting various …
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The role of post-transcriptional regulators in pathogenesis and secondary metabolite production in Serratia sp. ATCC 39006.
… produces two secondary metabolite antibiotics, prodigiosin and a carbapenem, and the plant cell wall degrading exoenzymes, pectate lyase and cellulase. A complex regulatory network controls production of prodigiosin, including a quorum sensing (QS) system, and the role of post-transcriptional …
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Novel pleiotropic regulators of gas vesicle biogenesis in Serratia
… 1-carbapen-2-em-3-carboxylic acid (car) and prodigiosin. It displays different motility mechanisms, such as swimming and swarming aided by flagellar rotation and biosurfactant production. In addition, S39006 produces gas vesicles to float in aqueous environments and enable colonization of …
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Characterisation of pleiotropic regulators of gas vesicle biogenesis, antibiotic production, motility and virulence in Serratia sp. ATCC 39006
… (a carbapenem) and the bioactive red pigment prodigiosin (a prodiginine). It is also the only known enterobacterium which naturally produces intracellular gas vesicles (GVs), enabling cells to float in static water columns. These hollow proteinaceous organelles are expressed from a 16.6 kb …
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Novel regulators of antibiotic biosynthesis in Serratia sp. ATCC 39006
… metabolites, particularly two antibiotics – prodigiosin and a carbapenem. Both compounds are tightly regulated in response to various physiological and environmental signals, including quorum sensing. This project aimed to identify and characterise new regulatory genes that modulate …
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Novel pleiotropic regulators of flotation, secondary metabolite production, and virulence in Serratia sp. ATCC 39006
… tripyrrole, 2-methyl-3-pentyl-6-methoxyprodigiosin (prodigiosin; a prodiginine). It also produces plant cell wall degrading enzymes (PCWDEs) and is capable of flagellar-mediated swimming and swarming motility. S39006 is the only enterobacterium known to naturally produce gas vesicles …
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The interplay between pathogenic bacteria and bacteriophage Chi: New directions in motility and phage-host interactions in Enterobacterales
… an increase in the production of the red pigment prodigiosin. Overall, our hypothetical model for χ infection is as follows: χ binds to the flagellum of its host using its single tail fiber, composed of monomers of the CHI_31 gene product gp31. This tail fiber interacts with CTD2 of flagellin, and …