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Showing 1 to 4 of 4 for “"primitive hematopoiesis"”.
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Runx1 in Primitive Hematopoiesis and Characterization of Hematopoietic Stem Cells in a Mouse Chronic Inflammatory Arthritis Model
… throughout adult life. Two different aspects of hematopoiesis are addressed in this dissertation. I. <underline>The regulation of primitive hematopoiesis by Runx1 and TGF-beta signaling.<underline> Primitive hematopoiesis, occurring exclusively in the yolk sac, is characterized by its transient …
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Valproic Acid Disrupts Hematopoiesis in Xenopus Laevis Through the Inhibition of Histone Deacetylase 3.
… and cellular functions. However, their role in hematopoiesis has not been determined, and in Xenopus laevis, a specific function for HDACs has yet to be identified. In the present work, we employed the class I selective HDAC inhibitor, valproic acid (VPA), to identify hdac3 as an essential …
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Genetic study of hematopoiesis development by two zebrafish mutants: Ugly duckling and tc-244
Hematopoiesis is defined as a biological process from which major lineages of blood cells are generated and subsequently mature into functionally active cells. Although it is widely known that vertebrate hematopoiesis has two phases: a primitive phase is followed by the other definitive phase, the …
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Heterogeneity, Origins, and Role of Omental Macrophages in Health and Early Tumor Seeding
… are innate immune cells that first appear at primitive hematopoiesis to facilitate fetal organ growth. After birth and depending on environmental cues, monocytes may replace a subset of embryonic-derived macrophages to differentiate into monocyte-derived macrophages. In the past several …