Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"primary motor cortex"”.
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Neural correlates of motor performance in primary motor cortex
… have characterized the behavior of cells in the primary motor cortex that correlate with movement of the upper limb. The patterns of behavior of cells before, during, and after the application of an external forcefield to the hand of a primate performing a motor reaching task have been described. …
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Distinct Populations of Layer 5B Pyramidal Neurons in the Primary Motor Cortex
<p>The ability of motor cortex to plan, execute, and refine different movements depends on the coordinated activity of many neurons found across its laminar structure. Layer 5b (L5b), a deep cortical layer that drives output signals from the cortex, contains excitatory pyramidal neurons that …
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Neural correlates of motor learning/memory in primary motor cortex of macaque monkeys
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1998.
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The impact of primary motor cortex, spinal cord, and sciatic nerve cooling on spinal reflex activity in the rat: a reversible deactivation study
… various parts of the reflex pathway, namely the primary motor cortex, spinal cord, and sciatic nerve, are incompletely known. This study aims to consider each of these to develop a better understanding of how spinal cord reflexes and the relationship between the central and peripheral nervous …
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Technologya nd Protocolsf or Translational Researchin ElectricalS timulation
… membrane potentials. Neuromodulation of the cortex using direct current (DC) stimulation may be a viable treatment for neurological disorders, enhancing cognitive function as well as facilitating neural plasticity. Theoretically, tDCS can employ many electrodes montages to emphasize …
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Alternating Current Stimulation for Essential Tremor
… cerebellum, red nucleus, thalamus, and cerebral cortex. Tremor generation in essential tremor is believed to be linked to neurodegeneration, abnormalities in a central oscillatory network, or dysfunction of the inhibitory neurotransmitter gamma-aminobutyric acid. Current treatments for essential …
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Investigating the Sophistication of Long-Latency Stretch Responses During Postural Control of the Upper Limb
A recent theory of motor control, based on optimal feedback control, posits that voluntary motor behaviour involves the sophisticated manipulation of sensory feedback. Although this theory can explain how people move in the world, it does not specifically describe how this control process is …
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Investigation of Endogenous Retroviruses in the Pathogenesis of Sporadic Amyotrophic Lateral Sclerosis (ALS) by
… transcripts were reported as elevated in premotor cortex samples from an ALS American cohort by Li et.al. (2015) the RT-qPCR assays performed in this sudy, using the same primers and reaction conditions in a larger ALS UK cohort were unable to corroborate these findings. Our collaborators at …
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Role of the precentral cortex in adapting behavior to different mechanical environments
… movement. With repeated experience, sensorimotor maps are adapted to maintain a high level of movement performance regardless of the mechanical environment. This dissertation explored the contribution of the precentral cortex to this process of motor adaptation. In the first experiment, we …
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Virtual reality visual feedback and its effect on brain excitability
… of distinct neural networks in the sensorimotor cortex. The objective is to explore neural responses to visual feedback of motor activities performed in complex virtual environments during functional magnetic resonance imaging (fMRI), and to identify sensory manipulations that could further …
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Neural Adaptation and the Effect of Interelectrode Spacing on Epidural Electrocorticography for Brain-Computer Interfaces
… monkeys with the electrode array centered over primary motor cortex: M1). Monkeys were then trained to perform a one-dimensional BCI task. The BCI control scheme was independent of any prior screening for task-related activity. All three monkeys successfully learned to perform the task with …
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Cortical Control of Naturalistic Facial Expression Production in Primates
… cortical face representations, including primary (M1), ventral premotor (PMv), and cingulate motor (M3) cortices. Much like their human counterparts, macaques use facial expressions to navigate both cooperative and competitive interactions with conspecifics. Yet despite their integral role …
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Development of and proposed applications for tetrodes in functional mapping of rodent sensorimotor striatum
… to three control tasks with similar sensory, motor and motivational aspects but different learning and memory requirements, and to localize task-responsive units with respect to striosomes and body part areas identified by neuronal responses to cutaneous stimulation/passive manipulation and …
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On the neuronal processing of movement dynamics
… collects five essays on how neurons in four motor areas of the frontal lobe process the movement dynamics. In the experiments described, monkeys executed visually instructed reaching movements while holding the handle of a robotic arm. Motors attached to the robot allowed turning on and off …
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Mitochondrial response to axonal injury
… an autophagosomal marker, was injected into primary motor cortex, to label the corticospinal tract (CST), of adult rats. The axons of the CST were then injured by dorsal column lesion at C4-C5. We found that mitochondria in injured CST axons near the injury site are fragmented and …
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Determining the optimal paradigm for investigating if M1 activations associated with step tracking wrist movements are direction or muscle related using EEG
… whether activations detected within the primary motor cortex (M1) during a wrist step tracking task encoded movement direction or specific muscle groups used to achieve the movement. This will provide information on the processes which occur within M1 of the human brain. Experiments were …
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The Long-Term Teratogenic Effect of Prenatal Alcohol Exposure on the Somatosensory and Motor Cortex of Rats
<p>The primary goal of this dissertation was to examine the long-term effect of prenatal alcohol exposure (PAE) on the primary somatosensory (SI) and primary motor cortex (MI). For over 30 years, PAE has been shown to produce a triad of symptoms (growth deficits, craniofacial dysmorphologies and …
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Transcranial Direct Current Stimulation with Individualized Physical Therapy for Chronic Knee Pain
… group had anodal tDCS (20 minutes) targeting the primary motor cortex of the involved knee. Safety was monitored by recording adverse events, and through a safety questionnaire given to participants with knee pain. Feasibility was evaluated by tracking recruitment, enrollment, and retention. …
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Neural representations of movement planning within the human prehension system
… and non-delayed movement planning in human primary motor cortex and examine how movement representations unfolded throughout the different stages of planning and execution. Overall, our findings expand previous understanding of the regions implicated in movement planning and offer new …
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