Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"primary bronchial epithelial cells"”.
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The development of novel strategies to modulate epithelial sodium channel (ENaC) activity in chronic obstructive pulmonary disease (COPD)
… αENaC small interfering RNA (siRNA) cargo into primary bronchial epithelial cells (PBECs). RALA/siRNA nanoparticles were well-tolerated by submerged PBECs and transfection of cells led to a high level of αENaC mRNA knockdown. Whilst local delivery to PBEC cultures at air-liquid interface (ALI) …
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Neuroinflammatory consequences of rhinovirus infection in the human airway
… from differentiation of human dental pulp stem cells towards a neuronal phenotype, termed peripheral neuronal equivalents (PNEs). PNEs were infected for 2, 6, 24, 48 and 72 hrs with major group RV-A16, or minor group RV-A1b, at a range of multiplicities of infection (MOI) (0.01 – 100). Primary …
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ATP, TRP channels and airway neuronal sensitisation
… (TRP) channels in chronic cough by working with primary bronchial epithelial cells (PBECS) and an in-Vitro human sensory neuronal model differentiated from human dental pulp stem cells termed peripheral neuronal equivalents (PNEs). TRP channels are thought to play a role in the neuronal …
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Mechanisms of virus infection of human airway epithelium cultured at an air-liquid interface (HAE-ALI)
ABSTRACT Polarized human airway epithelial (HAE) cultures are instrumental for studying respiratory tract diseases and gene delivery of airways. Primary epithelial cells isolated from tracheobronchial airways, grown in transwell at an air-liquid interface (ALI), undergo media-induced mucociliary …
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Regulation of cAMP-Dependent Gene Expression in Airway Epithelial Cells: A Transcriptional and Pharmacodynamic Analysis
… functions. In the BEAS-2B airway epithelial cell line and in human primary bronchial epithelial cells (HBEC), the LABAs, indacaterol and salmeterol, promoted robust transcriptional responses. Functional annotation and gene ontology analyses identified genes with both …