Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"prexasertib"”.
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TARGETING THE DNA DAMAGE RESPONSE PATHWAY FOR THE TREATMENT OF AGGRESSIVE THYROID CANCERS, IN VITRO STUDIES
… the effect of a selective Chk1 kinase inhibitor, Prexasertib (PX), currently employed in ongoing phase II clinical trials for other cancers treatment, which was used to treat cell lines either alone or in combination with DX or LENV. Flowcytometry analysis was used to evaluate cell cycle …
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Medulloblastoma: New animal models, preclinical drug testing, and characterising immune infiltrates
… cycle checkpoint kinase inhibitor (LY2606368, prexasertib) as a novel approach in the treatment of Group 3 medulloblastoma. Combination GEM/LY2606368 treatment improved the survival of mice with aggressive medulloblastoma. Using immunoblotting and flow cytometry I showed that mechanistically …