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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 3 of 3 for “"pretargeting"”.

  1. The Development of Novel Platforms for the Imaging of Cancer by Positron Emission Tomography

    Cook, Brendon EThe Graduate School and University Center of The City University of New York2020

    … (Tz) and a <em>trans</em>-cyclooctene (TCO) for pretargeting. By separately injecting antibody and radioligand and allowing the two to “click” <em>in vivo</em>, overall dose to the patient can be reduced nearly 45-fold. The first half of the dissertation to follow seeks to optimize both antibody …

    cuny-grad Repository record

  2. The Development of Novel Radioimmunoconjugates for the PET Imaging and Radioimmunotherapy of Cancer

    Sarrett, Samantha MThe Graduate School and University Center of The City University of New York2023

    … click reaction for diagnostic and therapeutic pretargeting; an overall introduction to antibodies in nuclear medicine; and a review based on the role of click chemistry and its advances in recent years.</p>

    cuny-grad Repository record

  3. A Pretargeted Spect Imaging Strategy Employing Technetium-99M Based on Bioorthogonal Diels-Alder Click Chemistry

    Walsh, Justin HThe Graduate School and University Center of The City University of New York2020

    … complexes were synthesized and tested for use in pretargeting SPECT imaging that utilizes the bioorthogonal Diels-Alder click reaction between tetrazine (Tz) and transcyclooctene (TCO). The objective was to optimize the excretory pathways of the <sup>99m</sup>Tc-peptide complexes for maximum tumor …

    cuny-grad Repository record