Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"pressurized metered-dose inhalers"”.
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Design Of Functional Dendrimer Nanocarriers And Their Formulations In Propellant-Based Inhalers For Pulmonary Drug Delivery
… two of the major challenges in developing pressurized metered dose inhalers for pulmonary drug / gene delivery to and through the lungs. First challenge is to design biocompatible moieties for the steric stabilization of suspension formulations in HFO-based propellants. Using a combination …
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Polymeric nanocarriers for the regional and systemic delivery of therapeutics to and through the lungs
… the aforementioned PNCs in portable, inexpensive pressurized metered dose inhalers (pMDIs).</p>
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Numerical Analysis of Respiratory Aerosol Deposition: Effects of Exhalation, Airway Constriction and Electrostatic Charge
… Charges consistent with standard pharmaceutical pressurized metered dose inhalers and dry powder inhalers were considered. The numerical predictions indicated that charged aerosols deposit as if they were 5 – 85% larger due to electrostatic effects. Applications of the studies considered include …
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Polymeric Nanocarriers And Their Oral Inhalation Formulations For The Regional Delivery Of Nucleic Acids To The Lungs
… and non-invasive route for targeting the lungs. Pressurized metered-dose inhalers (pMDIs), are the most commonly used OI in treatment of lung diseases and are thus promising OI devices to be used for the delivery of nucleic acids to the lungs. However, progress in the development of pMDI …
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INFLUENCE OF ELECTROSTATIC CHARGE UPON THE DEPOSITION BEHAVIOR OF PHARMACEUTICAL AEROSOLS WITHIN CASCADE IMPACTORS
… distribution (APSD) of commercially available pressurized metered dose inhalers (pMDIs) within the Electrical Low Pressure Impactor (ELPI) was examined. Electrostatic properties were modified using an external voltage source in conjunction with the ELPI corona charger and observed to be …