Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"prenatal exposure"”.
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Behavioral Changes in Adult C57BL/6J Mice following Prenatal Exposure to Ethanol.
… research indicates that timing of alcohol exposure of the embryo/fetus is a critical determinant of the behavioral deficits associated with FAS. This study represents a model for binge drinking, in which C57BL mouse embryos were exposed to alcohol during 2 separate critical periods of brain …
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Prenatal exposure to di-(2-ethylhexyl) phthalate (DEHP) affects reproductive outcomes in mice
Made available in DSpace on 2015-01-21T19:48:35Z (GMT). No. of bitstreams: 2 Sarah_Steinmann.pdf: 3164394 bytes, checksum: 328ad683ab1c9c5ace3db3f526440b41 (MD5) MS Thesis.docx: 4955493 bytes, checksum: c6340d08f5b331a08772527c673f9a8c (MD5)
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Prenatal exposure to phthalates accelerates reproductive aging in multiple generations of female mice
… health, and bone health. Many studies focus on exposure to single phthalates, but humans are exposed to mixtures of many different chemicals, including phthalates, on a daily basis. Therefore, studies are needed to examine if an environmentally relevant phthalate mixture may be negatively …
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Prenatal exposure to maternal obesity and SFLT-1 overexpression and cardiovascular function in the adult offspring
… cardiovascular diseases; however, the effects of prenatal development cannot be overlooked. In the 1980s Barker proposed a hypothesis that poor nutrition in the fetal or early neonatal period increases susceptibility to the negative effects of an affluent diet during adulthood. Overall, there is …
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Evaluating the relationship between prenatal exposure to acetaminophen and phthalates and early attention and language development
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2023-12-01
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The neurostructural effects of prenatal exposure to methamphetamine in an infant population in the Western Cape
Prenatal methamphetamine exposure is associated with functional and neurostructural alterations, but neuroimaging investigations of these effects in infants are almost non-existent. Studies in neonates permit a degree of separation of drug exposure effects from potential confounders in the …
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Prenatal exposure to di-(2-ethylhexyl) phthalate and high-fat diet synergistically disrupts mouse fetal oogenesis and affects folliculogenesis
… dermal contact, and during medical procedures. Exposure to DEHP alters ovarian function in humans. Additionally, foods high in fat content, regularly found in the western diet, are potential disruptors of fetal ovarian function. Due to DEHP’s high lipophilicity, high-fat foods can be easily …
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MATERNAL USE OF PSYCHIATRIC MEDICATIONS DURING PREGNANCY AND ADVERSE BIRTH OUTCOMES AND NEURODEVELOPMENTAL PROBLEMS IN OFFSPRING
Understanding consequences of prenatal exposure to psychiatric and analgesic medications is important because use of these medications among pregnant women is relatively common and increasing. Rodent experiments have shown effects of perinatal exposure to specific medications; however, these …
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Environmental Toxins and Essential Trace Elements at Delivery and ADHD
… to investigate the relationship between prenatal exposure to these chemicals and attention deficit hyperactivity disorder (ADHD) in childhood. The study base comprised children born in Malmö, Sweden, between 1978 and 2000 that were followed up until 2005. Children with ADHD (n=206) were …
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Impacts of prenatal phthalate and bisphenol exposure on infant cognition and early language development
The neurodevelopmental impacts of prenatal exposure to endocrine disrupting chemicals including bisphenols and phthalates are a growing public health concern. Bisphenols and phthalates are used in plastic consumer products, food and drink packaging and containers, personal care and household …
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The effects of an environmentally relevant phthalate mixture on female reproduction
… urine and blood samples, suggesting ubiquitous exposure to different phthalates. Studies have shown that women are exposed to phthalates at higher levels compared to men, likely due to the higher use of products by women compared to men. This ubiquitous exposure to phthalates is of great concern …
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Tissue segmentation of the cerebellum from MR images
The cerebellum is known to be very susceptible to prenatal exposure to alcohol and people affected by Fetal Alcohol Spectrum Disorder (FASD) show a decrease in cerebellar volume. Unfortunately, there seems to be little work that focuses specifically on cerebellum tissue segmentation. We set out to …
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Relation between reported maternal caffeine consumption during pregnancy and neonatal state and heart rate
The prenatal period is a time of rapid development during which the fetus adapts to a wide range of experiences that may alter the infant’s developmental course. These experiences include exposure to conditions such as maternal stress, disease and the ingestion of a wide range of drugs. While great …
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Effects of prenatal alcohol exposure on cerebellar volume in children an MRI study
Years of research have demonstrated that prenatal exposure to alcohol contributes to a range of effects in exposed children. These include problems in attention and hyperactivity, deficits in memory and learning, and problems with social, as well as emotional development. Past research has …
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Exploring language production, comprehension and naming in adolescents with fetal alcohol spectrum disorders
… and naming in children with moderate or heavy prenatal exposure to alcohol, and ii) to determine if these domains are a specific weakness in these children. The study compared 25 children with FASD to 25 typically developing non-alcohol exposed controls on four language measures; (1) the …
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Neonatal Abstinence Syndrome: A Systematic Review and Meta-Analysis of Neurocognitive Outcomes for Infants Born with Neonatal Abstinence Syndrome
… in NAS incidence in the United States. Infants prenatally exposed to opioids have been associated with negative health outcomes for infants and mothers, but its long-term neurologic development remains unknown. This study examined the association between prenatal exposure to opioids and …
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Prenatal Environmental Stressors Impair Postnatal Microglia Function and Adult Behavior in Males
… gestation, as a model of air pollution exposure. This exposure is combined with nest material restriction during the last trimester of gestation to induce stress. I found that combined prenatal exposure to air pollution and maternal stress induced maternal immune activation in pregnant …
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Impact on Endogenous Neural Stem Cells and Neurogenesis by Drugs of Abuse: From Fetal Neurodevelopment to the Adult Brain
… and subsequent differentiation, during adult or prenatal exposure. Recently, there has been an increase in the number of prescriptions written for opioids, leading to the current opioid epidemic. Further, prescription opioid use by women during pregnancy has risen dramatically since 2004. This …
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Impact of prenatal maternal stress on infant cognition and modifications of effects by exposure to phthalates
Recent literature has shown that maternal exposures to both chemical and non-chemical stressors during gestation are risk factors for adverse neurodevelopment. However, there is little evidence on the impact of these, individually or in combination, on cognitive development during the first year of …
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