Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"prenatal alcohol exposure (PAE)"”.
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Prenatal alcohol exposure-related reading and phonological processing deficits mediated by working memory
… studies have investigated the effects of prenatal alcohol exposure (PAE) on reading ability and/or on phonological processing. Most published studies have only included measures of single-word reading. This choice means those studies may lack ecological validity in that they might not have …
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Dysregulation of Immune Function, Gut Microbiota Composition and Short-Chain Fatty Acid Production Following Prenatal Alcohol Exposure: A Developmental Perspective
Prenatal alcohol exposure (PAE) severely impacts fetal development, including alterations to the developing immune system. Immune perturbations, in tandem with gut dysbiosis, have been linked to brain and behavioural dysfunction, but this relationship is poorly understood in the context of PAE. …
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The Life Stories of Individuals Who as Adults Were Identified as Experiencing the Effects of Fetal Alcohol Spectrum Disorder
The teratogenic effects of prenatal alcohol exposure (PAE) can cause irreversible physical and neurological impairments that are present at birth and can have lifelong implications (McGee & Riley, 2007). One’s capacity to interact productively and effectively with one’s surroundings can be …
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Impact of Prenatal Alcohol Exposure on Cognition and Inflammation in Aging Male and Female Rats: A Longitudinal Approach
Prenatal alcohol exposure (PAE) is a serious global health concern that can have long-lasting detrimental effects on the developing brain and behaviour. However, less is known about the effects of PAE as an individual ages into middle and old age. Here, we investigate the long-term effects of PAE …
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Amygdala and Prefrontal Cortex Macrostructure and White Matter Microstructure Development in Typical and Atypical Children and Adolescents
… developing populations, such as those with prenatal alcohol exposure (PAE), as they may explain behavioural challenges, including elevated sensation-seeking. I used T1 and diffusion-weighted magnetic resonance imaging and generalized additive mixed effects models to characterize amygdala and …
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Neuroimaging study of prenatal alcohol exposure effects on structural and functional connectivity in children
Fetal alcohol spectrum disorders (FASD) describe the spectrum of cognitive, behavioural and neurological impairments associated with prenatal alcohol exposure (PAE). Diffusion tensor imaging (DTI) and resting-state functional MRI (rs-fMRI) were used to assess effects of PAE on microstructural …
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Neuroimaging and behavioral investigation of declarative memory in South African children prenatally exposed to alcohol
Prenatal alcohol exposure (PAE) is associated with a range of physical, growth, and neurobehavioral deficits characteristic of individuals with fetal alcohol spectrum disorders (FASD). Although declarative memory impairment is a key feature of the neurocognitive profile of FASD, the mechanisms …
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A study of event-related electrocortical oscillatory dynamics associated with cued motor-response inhibition during performance of the Go/NoGo task within a sample of prenatally alcohol-exposed children and age-matched controls
Fetal alcohol spectrum disorders (FASDs) are a spectrum of disorders that occur due to prenatal alcohol exposure (PAE). Response inhibition refers to the ability to inhibit/suppress a prepotent behavioural tendency set in motion during an experimental task. Our research explored neocortical …
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Social cognition in South African children with Fetal Alcohol Spectrum Disorders
… the social-cognitive profile of individuals with prenatal alcohol exposure (PAE) has confirmed poorer social skills in these children compared to healthy controls, independent of overall cognitive functioning. However, although children with fetal alcohol spectrum disorders (FASD) are known to …
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Tissue Parameter Mapping in Children with Fetal Alcohol Spectrum Disorders
Background: Fetal alcohol spectrum disorders (FASD), which are caused by prenatal alcohol exposure (PAE), affects people around the world. Certain communities in South Africa have among the highest reported incidences of fetal alcohol syndrome (FAS) in the world. Although PAE-related brain …
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Attachment and Emotion Regulation in Adolescents with FAS-Dysmorphism
Children with fetal alcohol spectrum disorders (FASD) are frequently reported by caregivers and teachers to have difficulties in socio-emotional functioning. It has been suggested that deficits in emotion regulation underlie these deficits in socio-emotional functioning. Children with prenatal …
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Prenatal alcohol exposure and the early neurodevelopmental outcomes of children in a South African birth cohort study
Introduction: Over the last few decades, prenatal alcohol exposure (PAE) has been a major public health problem both globally and in low- to-middle-income countries (LMICs) such as South Africa. Pregnant women and new mothers are particularly vulnerable; and PAE may be associated with adverse child …
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Differences in callosal and subcortical volumes and associated neurobehavioural deficits in children with prenatal alcohol exposure
… Province of South Africa where heavy maternal prenatal alcohol consumption is perpetuated by historical and societal challenges, have some of the highest prevalence rates of fetal alcohol syndrome (FAS) in the world. FAS has lifelong behavioural and cognitive consequences. Neuroimaging research …
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The impact of traumatic childhood experiences on cognitive and behavioural functioning in children with foetal alcohol spectrum disorders
Prenatal alcohol exposure (PAE) can cause lasting physical damage to the developing foetusincluding the brain. This brain damage can manifest as cognitive dysfunction and behaviouraldifficulties, which can be diagnosed as foetal alcohol spectrum disorders (FASD). FASD is thought tobe common in the …
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The morphology of the intraparietal sulcus in children prenatally exposed to alcohol in a sample of children from the Western Cape, South Africa and its potential relationship with number processing
… play a critical role in number processing. Fetal alcohol spectrum disorders (FASD) result from prenatal exposure to alcohol and are particularly prevalent in the Western Cape region of South Africa. Arithmetic is a domain of cognitive function that is particularly sensitive to prenatal alcohol …
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Preliminary evidence that prenatal maternal choline supplementation protects the white matter microstructure of infants born to heavy-drinking women
Prenatal alcohol exposure (PAE) is the most widespread preventable cause of neurocognitive and neurodevelopmental disabilities worldwide, known collectively as fetal alcohol spectrum disorders. It has been shown in a small double-blind, randomized choline supplementation trial that prenatal …
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The Long-Term Teratogenic Effect of Prenatal Alcohol Exposure on the Somatosensory and Motor Cortex of Rats
… was to examine the long-term effect of prenatal alcohol exposure (PAE) on the primary somatosensory (SI) and primary motor cortex (MI). For over 30 years, PAE has been shown to produce a triad of symptoms (growth deficits, craniofacial dysmorphologies and central nervous system …