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Showing 1 to 2 of 2 for “"premature coronary artery disease"”.

  1. The Best Practice Guideline for Early Detection and Treatment of Heart Disease In Asymptomatic Adults with a Family History of Premature Coronary Artery Disease

    … cause of death in the United States, heart disease remains a priority for targeted measures for early detection and treatment. Family history of premature CAD has been well documented as a significant independent risk factor for over two decades, with an increased threat of sudden coronary

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  2. Smooth Muscle Cell Stress Response: Essential in Atherosclerotic Pathogenesis

    … α-actin (SM α-actin), predispose to premature coronary artery disease (CAD).</p> <p>In this dissertation, I conducted an in-depth analysis on the SMC stress response in atherosclerosis formation in vivo. We found that SMC-specific deletion of Perk in hyperlipidemic mice reduces …

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