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Showing 1 to 2 of 2 for “"pregnanolone"”.

  1. Investigation of two Interacting Neurosteroid Sites on a GABA Receptor by Mutagenesis and Mathematical Modeling

    … by the neurosteroids pregnenolone sulfate and pregnanolone, identifying neurosteroids as potential lead compounds. Notably, neurosteroid sites are non-conserved between invertebrates and mammals, limiting possible cross-toxicity. This proposal is focused on better understanding neurosteroid …

    ohiolink Repository record for Investigation of two Interacting Neurosteroid Sites on a GABA Receptor by Mutagenesis and Mathematical Modeling (opens in a new tab)

  2. The action of ovarian steroids on the hypothalamic LHRH pulse generator

    … a 5$\beta$,3$\beta$ progesterone metabolite (pregnanolone) shares the stimulatory action upon the hypothalamic LHRH neural apparatus with its mother molecule and that this stimulatory action of progestins is through noradrenergic neurotransmission.

    uiuc Repository record for The action of ovarian steroids on the hypothalamic LHRH pulse generator (opens in a new tab)