Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 553 for “"prefrontal"”.
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Dopaminergic modulation of prefrontal cortex subpopulations
… abundant evidence that dopamine modulates medial prefrontal cortex (mPFC) activity to mediate diverse behavioral functions, the precise circuit computations remain elusive. One potentially unifying theoretical model by which dopamine can modulate functions from working memory to schizophrenia is …
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The connectivity of the mammalian prefrontal cortex
The fine scale connections of prefrontal cortex (PFC) were investigated in the rat brain, in order to determine organizational properties of PFC pathways which were previously undefined. Neuroanatomical tract tracers (Fluro-Gold, Fluoro-Ruby, Fluoro-Emerald, Biotinylated dextran amines; Fluorescein …
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Binge Alcohol Effects on the Prefrontal Cortex
… and decision making of daily life. Loss of prefrontal grey matter resulting from heavy alcohol consumption has been documented, however this volume loss does not appear to be caused by a decrease in the number of prefrontal cortex neurons. This study aimed to determine whether the medial …
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PREFRONTAL ACTIVITY IN COGNITIVE FUNCTION: MECHANISMS AND MATURATION
… functions are thought to be controlled by the prefrontal cortex, which itself undergoes a number of anatomical and functional changes that last beyond adolescence, into early adulthood. The nature of these changes is poorly understood. Experiments in this dissertation investigated behavioral …
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Multi-item memory in the primate prefrontal cortex
… the activity of neurons from the lateral prefrontal cortex during task performance. We found that the majority of neurons showed delay activity that depended on the identity of both images (a minority reflected just one image), and that activity related to a given combination of images was …
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Variability of Neural Responses in the Lateral Prefrontal Cortex
… which the stimulus is absent. The dorsolateral prefrontal cortex has long been implicated as the seat of visuospatial working memory, and undergoes dramatic increases in volume and functional connectivity during and around the time of puberty. However, much of the neurophysiological changes …
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Chronic Stress Effects on Prefrontal Cortical Structure and Function
… structural and functional abnormalities in the prefrontal cortex. In three parallel rodent and human neuroimaging studies, this project assessed the effects of chronic stress on prefrontal cortical structure and function and the behavioral correlates of these changes. The first study used fMRI …
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Processing of relevant information in the primate prefrontal cortex
… ventral to the principal sulcus of the lateral prefrontal (PF) cortex in two monkeys (macacca mulatta). Activity was assessed during the performance of three visual memory tasks. In the first task, the sensory and mnemonic receptive fields were studied, by requiring monkeys to simultaneously …
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Role of rat medial prefrontal cortex in time interval estimation
… lines of evidence suggest the involvement of prefrontal cortex in time interval estimation. The underlying neural processes are poorly understood, however, in part because of the paucity of physiological studies. The goal of this study was to test the requirement of intact medial prefrontal …
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Controlling memory and resolving interference : prefrontal contributions to flexible behavior
… finding of activation in ventrolateral prefrontal cortex (VLPFC) during task switching. These observations motivate the hypothesis that left VLPFC may resolve proactive interference arising from long-term memory during a task switch. Chapters 2 and 3 describe three fMRI experiments …
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Investigating prefrontal cortex neuronal signatures of opioid-induced risk-taking behavior
… neural signals of risky opioid seeking in the prefrontal cortex, a region implicated in executive decision-making. Following morphine conditioned place preference, rats underwent a conflict test in which fear-inducing cat odor was introduced in the previously drug-paired side of the apparatus. …
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Impact of Acute Ethanol Injections on Medial Prefrontal Cortex Neural Activity
The medial prefrontal cortex (mPFC) is a cortical brain region involved in the evaluation and selection of motivationally relevant outcomes. mPFC-mediated cognitive functions are impaired following acute alcohol exposure. In rodent models, ethanol (EtOH) doses as low as 0.75 g/kg yield deficits in …
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The role of the prefrontal cortex in hypnotic and placebo analgesia.
… and that whilst placebo effects rely on the prefrontal cortex (PFC; Benedetti, 2010), the role of the PFC in hypnosis and hypnotic suggestibility is inconclusive. Methods: Fifty-four participants (27 male) performed tasks known to tap either left (the Stroop Task; Stroop, 1938), right (the …
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An fMRI Analysis of Dorsolateral Prefrontal Cortex's Involvement in Attentional Control
The present work also addressed the proposal that DLPFC and anterior cingulated cortex (ACC) play complementary roles in control. Through an analysis of practice-related effects, the present work provided support for the notion that DLPFC is involved in implementing control while ACC is involved in …
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Prefrontal cortical organization of executive function in depression and comorbid anxiety
Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2012-06-21T17:44:45Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 2 Warren_stacie.docx: 644889 bytes, checksum: 923640304f115dea42a20156cb65b80e (MD5) Warren_Stacie.pdf: 999234 bytes, …
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The Impact of Early Life Adversity on Mediodorsal Thalamic-Prefrontal Cortex Maturation
… of cognitive and affective behaviors is the prefrontal cortex (PFC) which receives inputs from various brain regions, including the mediodorsal thalamus (MD), and undergoes a protracted maturation. Thus, it’s conceivable that ELA exposure during a sensitive window of MD development may …
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