Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 33 for “"prednisolone"”.
-
Stereoisomeric Prodrugs to Improve Ocular And Oral Absorption of Prednisolone
… prodrugs such as Lvaline- D-valine-prednisolone (LDP) and D-valine-L-valine-prednisolone (DLP) to improve ocular and oral absorption of prednisolone. These prodrugs have been examined for their interaction with various influx and efflux transporters commonly expressed on corneal and …
-
The Effectiveness of Camphorated Paramonochlorophenol, Metacresyl Acetate, and Prednisolone in Combination as an Antimicrobial Agent
… paramonochlorophenol, metacresyl acetate, and prednisolone in combination is advocated to reduce the inflammatory potential of the germicide and thus reduce the occurrence of post-operative pain. It is imperative that a medicament retain antimicrobial activity while reducing inflammatory …
-
Effects of systemic flunixin meglumine, topical oxytetracycline, and topical prednisolone acetate on tear film proteinases innormal horses
… treatments, topical oxytetracycline, topical prednisolone acetate, and systemic flunixin meglumine, on the activity of two proteinases, matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9), in equine tear film. The study design consisted of twelve ophthalmically normal …
-
Bell's Palsy - Medical Treatment and Influence of Prognostic Factors
… was to evaluate the effect of treatment with prednisolone and/or valaciclovir in a large number of Bell’s palsy patients and study how prognostic factors such as age, severity of palsy at baseline, and time to treatment start may influence outcome. Data from the Scandinavian Bell’s Palsy Study …
-
A Quantitative Description of Anthelmintic and Prednisolone-Induced Alterations in the Ultrastructure of Hepatic Parenchymal Cells of the Beagle
Made available in DSpace on 2014-12-09T22:30:25Z (GMT). No. of bitstreams: 1 7013281.pdf: 3608332 bytes, checksum: d56206f5f06c71422a2384fa4edebf65 (MD5) Previous issue date: 1969
-
Crystal engineering, Bio Pharmaceutics and Cell biology of active pharmaceutical ingredient (drug) nanoparticles. Formation and cell interaction of hydrocortisone and prednisolone nanoparticles.
… of hydrophobic steroid drugs: hydrocortisone and prednisolone were produced. Nanosuspensions were prepared using a bottom-up approach: the anti-solvent precipitation method using microfluidic reactors. Surface modification was carried out on these nanosuspensions using cationic surfactants to …
-
A description of the pharmacokinetics of first line anti-tuberculosis drugs and adjunctive corticosteroid therapy in the pericardial compartment and their effect on cytokine profiles in the pericardial compartment of patients with tuberculous pericarditis
… Adjunctive corticosteroid therapy with prednisolone, has been shown to reduce the incidence of constrictive pericarditis by more than 50%. However, this is associated with significant side effects, especially in patients with HIV co-infection. Constrictive pericarditis is only partially …
-
THE DOUBLE BOND IN Δ1-2 POSITION OF STEROIDS: A MATTER OF CONTROVERSY IN THE CONTROL OF ILLICIT TREATMENTS OF FARM ANIMALS
… a two-year period of the frequent detection of prednisolone-positive bovine urine samples in the Italian region of Lombardy, studies were initiated to investigate the source. The problem of modifications in biological fluids was therefore evaluated also regarding a possible transformation of …
-
Development of a risk score for constrictive pericarditis using the Investigation of the Management of Pericarditis randomised clinical trial dataset
… and effusive-constrictive pericarditis. Although prednisolone treatment was associated with a reduced relative risk of constrictive pericarditis in high (risk ratio = 0.59; 95% CI = 0.378 – 0.925) and medium (risk ratio = 0.12; 95% CI = 0.016 – 0.971) risk individuals, prednisolone treatment did …
-
Analysis of clustered competing risks with application to a multicentre clinical trial
… the effectiveness and safety of adjunctive prednisolone and Mycobacterium indicus pranii immunotherapy, in reducing the composite outcome of death, constriction or cardiac tamponade, requiring pericardial drainage in patients with probable or definite tuberculous pericarditis. The clinical …
-
Immune responses to AAV gene therapy in the ocular compartment
… immune responses to AAV. It was found that prednisolone was effective at reducing anti-AAV neutralising and total AAV binding antibody titres. This effect may have occurred via the inhibition of splenic germinal center B-cell reactions and class-switching of immunoglobulin antibody isotypes, …
-
The use of novel poly(allylamine) based amphiphilic polymers for drug delivery.
… using five model hydrophobic drugs, propofol, prednisolone griseofulvin, etoposide and novel anticancer agent BNIPDaoct. The Ch5 and Dansyl10 showed excellent drug solubilisation capacities. At 6 mgmL-1 the Ch5 achieved propofol solubility 70-fold greater than its aqueous solubility, …
-
ΑΝΑΠΤΥΞΗ ΤΕΧΝΙΚΩΝ ΓΙΑ ΤΗ ΒΕΛΤΙΩΣΗ ΤΗΣ ΠΟΙΟΤΗΤΑΣ ΤΩΝ ΔΙΣΚΙΩΝ ΚΑΙ ΤΗΝ ΑΠΟΔΕΣΜΕΥΣΗΦΑΡΜΑΚΩΝ ΑΠΟ ΕΠΙΚΑΛΥΜΜΕΝΕΣ ΣΤΕΡΕΕΣ ΦΑΡΜΑΚΟΤΕΧΝΙΚΕΣ ΜΟΡΦΕΣ
… DRUGS (INDOMETHACIN, PHENYL-PROPANOLAMINE-HCL, PREDNISOLONE) DEPENDENT OR INDEPENDENT ON THE PH OF THE ENVIRONMENT.
-
The Nonenzymatic Modification of Proteins by Steroids and DNA by Reducing Sugars; In Vitro and In Vivo Studies
… the glucocorticoids; such as Cortisol and prednisolone, which contain side-chain ketols, and the estrogen metabolite 16α-hydroxyestrone (16αOHE), which contains a ring ketol. The long-term therapeutic administration of glucocorticoids is associated with many toxic manifestations and it was …
-
Epileptic Spasms: Evidence for oral corticosteroids and implications for low and middle income countries (Systematic Review)
… assess the quality of evidence of prednisone and prednisolone (oral corticosteroids) for the management of epileptic spasms. There is level C recommendation based on class III evidence to support the efficacy of oral corticosteroids for the acute clinical control of epileptic spasms and EEG …
-
Engineering delivery systems for the treatment of Non-Hodgkin lymphoma
… Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone), a commonly used therapeutic regimen for many Non-Hodgkin lymphomas. While therapeutic remission can occur in 50% - 80% of these patients, nearly half are expected to develop relapsing or refractory disease. There exists a clear …
-
Clinical evaluation of fibrotic idiopathic interstitial pneumonia
… disease behaviour were assessed in two studies. Prednisolone therapy was predictive of death at 12 months and 10% decline in FVC at 6 months, St George’s Respiratory Questionnaire score was predictive of death at 12 months. A prospective pilot study of 27 patients with IPF showed that CaNO has a …
-
Lipid Based Frameworks And Topical Ocular Inserts For The Delivery Of Small Molecule Therapeutics To The Posterior Segment Of The Eye
… (IN), ciprofloxacin hydrochloride (CIP) and prednisolone sodium phosphate (PSP). Transmembrane flux of IN, PSP and CIP were enhanced by ~3.5-folds, ~3.6-folds and ~2.9-folds, respectively, from the polymeric inserts when compared to the control formulations, post 3 h. Moreover, ocular inserts …
-
Pharmacokinetics of a novel cytosine arabinoside subcutaneous protocol in dogs with meningoencephalomyelitis of unknown etiology
… receiving only 1 oral IMD (either prednisone or prednisolone). Dogs with MRI and CSF findings compatible with an antemortem diagnosis of MUE weighing greater than 2.5 kilograms were recruited for this study, and 8 dogs met the inclusion criteria. Dogs received CA as a CRI (200 mg/m2 IV over 24h) …
-
The role and essence of pilot trials and subgroup analysis in cardiovascular research: the IMPI trial experience
… a priori on the modification of the effect of prednisolone by baseline pericardiocentesis status of trial participants is used to highlight the role subgroup analysis can play in unmasking the group effect in the randomised control trial. The thesis then goes on to present the preliminary …
Page 1 of 2