Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"predictive classification"”.
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A Study of the Minimum p-value and Related Methods for the Identification of Treatment-Sensitive Groups
… variable or biomarker, which is referred as predictive classification in this thesis. The clinical variable or biomarker used for predictive classification is usually continuous and, therefore, a cutpoint needs to be determined for the definition of the subgroup. The commonly adopted methods, …
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Feature selection and classification for high-dimensional biological data under cross-validation framework
… in selecting important predictors and to build predictive classification models. Traditionally, cross-validation methods have been used in order to determine the tuning or threshold parameter for the feature selection. We propose improvements over the methods by adding repeated and nested cross …
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Comparison of Event History Analysis and Latent Growth Modeling for College Student Perseverance
… the others in terms of predicting correct classification. Using event history analysis with the structural equation modeling framework, however, appeared to be a very promising alternative to event history analysis with logistic regression since one can model error term and examine the …
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A Knowledge Based Approach of Toxicity Prediction for Drug Formulation. Modelling Drug Vehicle Relationships Using Soft Computing Techniques
… to make original contributions to the field of predictive toxicology. The first part of this thesis provides a detailed scientific discussion on all aspects of drug formulation and toxicity. Discussions are focused around the principal mechanisms of drug toxicity and how drug toxicity is studied …
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A Knowledge Based Approach of Toxicity Prediction for Drug Formulation. Modelling Drug Vehicle Relationships Using Soft Computing Techniques
… to make original contributions to the field of predictive toxicology. The first part of this thesis provides a detailed scientific discussion on all aspects of drug formulation and toxicity. Discussions are focused around the principal mechanisms of drug toxicity and how drug toxicity is studied …
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Towards systems pharmacology models of druggable targets and disease mechanisms
… and costly attrition. Using text mining and text classification I present a growing landscape of systems pharmacology models in literature growing from humble roots because of step-wise increases in our understanding of biology. Furthermore, I develop a case for the capability of systems …