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Showing 1 to 11 of 11 for “"preconcentrator"”.
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Development of an integrated capillary valve-based preconcentrator and surface-based immunoassay
A new generation of integrated preconcentrator and immunoassay was developed. A novel, self-aligned method for patterning Nafion resin was developed and applied to create a preconcentrator. In a parallel effort, a surface-based immunoassay was developed and optimized for use with the …
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Nanoporous Silicon in Gas Preconcentration and Sensing
… end, the potential of nanoporous silicon as a ‘preconcentrator’ to solve some of these challenges is investigated, by adsorbing molecules inside the pores before releasing them in a pulse into a gas detector, improving its effective sensitivity. This technique is applied to vapour-phase …
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Investigations of and performance improvements in the mercury thiourea complex ion chromatography method for mercury speciation analysis
… HgII. In addition, it is shown that the system’s preconcentrator effectively traps both MeHg and HgII in samples containing strong Hg-binding ligands − 1 mM glutathione, thiosalicylic acid, and 0.15 M thiourea – giving it capabilities for rapid analysis of samples containing such ligands that the …
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Electrokinetic trapping of biomolecules : novel nanofluidic devices for proteomic applications
… development of a highly efficient nanofluidic preconcentrator, which can achieve a million fold detectability enhancements without complex buffer arrangements. This thesis also includes an integrated preconcentration-immunosensing device.
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Zebra GC: A Fully Integrated Micro Gas Chromatography System
… mixtures has been described. A microfabricated preconcentrator (microPC), a MEMS separation column with on-chip thermal conductivity detector (microSC-TCD), the flow controller unit, and all the necessary flow and thermal management as well as user interface circuitry are integrated to realize …
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Membrane-Based Protein Preconcentration Microfluidic Devices
… in poly(methyl methacrylate) (PMMA) formed the preconcentrator. When a voltage was applied between the sample reservoir and the ionically conductive membrane in a capillary-based system, R-phycoerythrin was concentrated more than 1,000 fold, as determined by laser-induced fluorescence …
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Nonlinear ion concentration polarization : fundamentals and applications
… of high-throughput, continuous-flow bio-agent preconcentrator by ICP. First, we describe the microscale ED model system for studying nonlinear ICP, which is used for visualizing in situ fluid flows and concentration profiles near IEMs. We verify that the nonlinear ICP largely determines ion …
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Microfluidic Columns with Nanotechnology-Enabled Stationary Phases for Gas Chromatography
… Similarly, miniaturization of key GC components (preconcentrator, separation column, detector, and pumps) using micro- and nanotechnology based techniques is an on-going research field. This dissertation specifically deals with the design, fabrication, coating, and chromatographic testing of …
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MicroGC: Of Detectors and their Integration
… The operation of this integrated device with a preconcentrator and in a matrix array was investigated. The more unique contribution of this research lies in the innovative discharge ionization detector. An ultra-low power, sensitive, easy to fabricate detector, it requires more investigation for …
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Chemical Micro Preconcentrators Development for Micro Gas Chromatography Systems
… method known as preconcentration. A micro preconcentrator (µPC) extracts the target analytes from the sample matrix, concentrates them, and injects them into the separation column for analysis. This work resulted in the development of silicon-glass bonded chips consisting of 7 mm x 7 mm x …
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Capillary Electrophoresis of Proteins with Selective On-line Affinity Monoliths
… accomplish this, an on-line protein G monolithic preconcentrator CE system for enrichment and separation of proteins was developed. This system proved effective for on-line sample extraction, clean-up, preconcentration, and CE of IgG in human serum. IgG from diluted (500 and 65,000 times) human …