Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 113 for “"prebiotic"”.
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Prebiotic assembly and replication of nucleic acids
… have been attempted under purportedly plausible prebiotic conditions in the laboratory. For example, polymerization of monomer units of RNA directed by base pairing interactions with an RNA template strand has been achieved in the absence of enzymes through a process called template-directed …
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Prebiotic photoreduction and polymerization of cysteinyl peptides.
… peptides likely played an important role in the prebiotic synthesis of cofactors, such as iron-sulfur clusters. However, cysteinyl peptides must be reduced in order to coordinate iron-sulfur clusters. Mixtures of ferric ions and cysteinyl peptides leads to the reduction of ferric to ferrous ions …
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Exploring hydrothermal reactions : from prebiotic synthesis to green chemistry
… at high temperature from the simple, probably prebiotic precursor formaldehyde. Indeed, this formose reaction could be carried out successfully, although the yield was lower compared to the counterpart reaction under ambient conditions. However, striking differences regarding selectivity and …
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Statistical Study of Chemical Reaction Network Models for Prebiotic Evolution
This thesis focuses on models of prebiotic evolution. The models abstractly describe chemical reaction networks and their dynamic evolution. The goal is to findquantitative measures of their generic features that can be used to identify lifelike systems in the solar system and on exoplanets, as …
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Understanding the Surface Induced Phosphorylation of Prebiotic Molecules by Schreibersite
<p>The study of the surface of a meteoritic mineral, schreibersite (Fe,Ni)<sub>3</sub>P, was investigated to provide insight into the role of the mineral’s surface in aqueous-phase phosphorylation reactions. The optimization of a custom-designed ultrahigh vacuum (UHV) apparatus and …
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Carbonyl Catalysis: Hydrolysis of Organophosphorus Compounds and Application in Prebiotic Chemistry
… the methodologies developed in Chapter 2 to prebiotic chemistry. A prebiotic-related aldehyde, glycolaldehyde was studied as the catalyst for the hydrolysis of organophosphorus compounds containing P(=O)-N bond, including phosphinic amides and phosphoramidates. Additionally, other prebiotic …
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Time-Restricted Eating and Prebiotic Supplementation in Young Adult Pediatric Cancer Survivors
… and acceptability of TRE with and without a prebiotic supplement in young adult PCS will be examined. Additionally, preliminary effects related to cardiometabolic risk will be explored. Finally, the preliminary effect of TRE with and without a prebiotic related the gut microbiome, metabolites …
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The prebiotic effects of amadumbe (Colocasia Esculenta) and okra (Abelmoschus esculentus) mucilage
Submitted in complete fulfilment for the Degree of Master of Applied Sciences in Food Science and Technology, Durban University of Technology, Durban, South Africa, 2023.
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Emergence, survival, and selection of metal-binding peptides in the prebiotic environment
… might have preceded modern metalloproteins. Such prebiotic, metal-binding motifs have been hypothesized to have existed through analyses of extant protein sequences. However, it is unclear how metal-binding motifs might have evolved in the harsh prebiotic environment. Here, we show how certain …
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An investigation of the prebiotic potential and gut health benefits of Irish seaweeds
… have now been proposed as a new source of prebiotics. Firstly, the bifidogenic potential of 15 Irish seaweeds was assessed using in vitro anaerobic fermentations. This investigation suggests that different Bifidobacterium species can utilise seaweed carbohydrates as their sole carbon source …
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Potential prebiotic roles of (amino-)acylation in the synthesis and function of RNA
… (acetyl-RNA). It was suggested that RNA emerged prebiotically via acetyl-RNA and also is proposed to have favourable genotypic properties due to greater propensity to form duplex structure. To study the properties of acetyl-RNA, their synthesis by solid-phase chemistry was required and described …
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Prebiotic supplementation with inulin and exercise influence gut microbiome composition and metabolic health
… unanswered related to the efficacy and role of prebiotics and exercise, and their respective influences on gut microbiome composition, intestinal permeability, insulin sensitivity and metabolic flexibility. Sedentary to recreationally active overweight and obese adults 40-75 years old at-risk …
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ENZYMATIC PRODUCTION OF PURIFIED ISOMALTOOLIGOSACCHARIDES PREBIOTIC PREPARATIONS AND THEIR FULL QUALITATIVE AND QUANTITATIVE CHARACTERIZATION
Prebiotics are non-digestible food ingredients that beneficially affect the host health by stimulating the growth and/or activity of one or a limited number of bacteria in the colon, and moreover can have systemic effects on metabolism regulation. Recent studies have pointed out the certain links …
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Isolation and characterization of prebiotic oligosaccharides from algal extracts and their effect on gut microflora
Submitted in partial fulfillment for the Degree of Master of Applied Sciences in Biotechnology, Durban University of Technology, Durban, South Africa, 2016.
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Dietary supplementation of a fiber-prebiotic-gut health promoter blend in extruded diets fed to dogs
… diet plays an important role in that. The use of prebiotics and dietary fibers have gained renewed interest in the pet food industry as a strategy to modulate gut health. Dietary fibers are heterogeneous compounds that exert different physiological responses and health benefits depending on their …
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High pressure processing (HPP) of kelulut honey (Sarawak): enhancement on the quality and alteration of prebiotic potential on lactobacillu
… beneficial compounds and has a potential of prebiotic. Conventional thermal treatments in honey industries caused more harm than good to thermolabile components in honey. Therefore, high-pressure processing (HPP) was chosen as it does not exert significant heat thus minimize any damaged done. …
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Evaluation of Prebiotic Fibers and Pectin on Probiotic Strains and Effect of Bacteriocin-like Substance on the Survival of Listeria Monocytogenes
<p>Probiotics and prebiotics have been shown to provide beneficial effects on the host health and there are numerous research efforts being conducted on a variety of specific applications. However, most prebiotic carbohydrates are lower molecular weight oligosaccharides; and the health benefits of …
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Assessing the Potential of Granular Activated Carbon Filters to Limit Pathogen Growth in Drinking Water Plumbing Through Probiotic Versus Prebiotic Mechanisms
Legionella pneumophila (Lp) and nontuberculous mycobacteria (NTM) are opportunistic pathogens that can be transmitted via drinking water, when tiny droplets containing the bacteria are aerosolized and inhaled during activities such as showering. The resulting respiratory illnesses, Legionnaires’ …
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Dietary Manipulation of Metabolic Function in the Human Gut Microbiome
… microbially accessible carbohydrates, termed prebiotics, is one mechanism by which SCFA production can be augmented or altered. While prebiotic therapies to increase SCFA in the gut have shown some promise in treating or preventing disease, treatment potential is limited by substantial …
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