Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"preadipocytes"”.
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Insulin and TSH signal transduction pathways in human preadipocytes.
… kinase (p70 S6K) pathway was examined in human preadipocytes in primary culture. The inhibitory effect of rapamycin on insulin-induced differentiation of preadipose cell lines has been attributed to a blockade of clonal expansion. We demonstrate that rapamycin inhibits the differentiation of …
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Comparative study of gene expression during the differentiation of white and brown preadipocytes
Einleitung Säugetiere haben zwei verschiedene Arten von Fettgewebe: das weiße Fettgewebe, welches vorwiegend zur Lipidspeicherung dient, und das braune Fettgewebe, welches sich durch seine Fähigkeit zur zitterfreien Thermogenese auszeichnet. Weiße und braune Adipozyten sind beide mesodermalen …
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An Investigation into the Role of Arf6 in MCH-mediated Rearrangements in 3T3-L1 Preadipocytes
Obesity has become a pandemic in our society. One potential method to alleviate this crisis is the use of pharmaceutical therapy to manage how our bodies metabolize the energy that we consume. Chronic overconsumption can lead to the activation of inflammatory responses and metabolic dysregulation, …
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Präadipozyten auf neuartigen Textilmatrizes
… possibilities, adipose tissue engineering with preadipocytes offers new perspectives. Essential requirements for successful reconstruction are: adequate threedimensional construct, autologous cells, ideal cultivation conditions and sufficient vascularization for further in vivo experiments. This …
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Overcoming wound healing complications following radiotherapy in human breast dermal fibroblasts, through the influence of preadipocytes from the stromal vascular fraction
… by immunocytochemistry and compared to human preadipocytes sourced commercially. The secretion of FGF, adiponectin and VEGF by the preadipocyte and the SVF mesenchymal cells was compared and the ability of their secretome to modulate dermal fibroblast proliferation, metabolism and migration …
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Overcoming wound healing complications following radiotherapy in human breast dermal fibroblasts, through the influence of preadipocytes from the stromal vascular fraction
… by immunocytochemistry and compared to human preadipocytes sourced commercially. The secretion of FGF, adiponectin and VEGF by the preadipocyte and the SVF mesenchymal cells was compared and the ability of their secretome to modulate dermal fibroblast proliferation, metabolism and migration …
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Optimierung der Proliferation und Differenzierung humaner Präadipozyten durch den Einsatz von humanem Serum
… solution is adipose tissue engineering with preadipocytes. These adipogenic precursor cells have the ability to proliferate and differentiate into adipose tissue after transplantation. This study aimed at developing an optimal protocol for proliferation and differentiation of preadipocytes. …
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Les effets de traitements aux acides gras polyinsatures omega-3 a longue chaine sur la secretion d'adiponectine de preadipocytes humains differencies
… secretion of adiponectin in differentiated human preadipocytes and determine if this effect is under the influence of PPARgamma nuclear receptors. Human adipocytes were exposed to 125muM of DHA or EPA for 24 h. Levels of adiponectin following DHA treatment increased from 0.19+/-0.02 to 0.22+/-0.01 …
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Mechanisms of growth hormone inhibition of adipose tissue growth
… in GH inhibition of differentiation of bovine preadipocytes. In this study, preadipocytes were isolated from subcutaneous fat of adult cattle and were induced to differentiate with or without GH. Based on Oil Red O staining, gene expression, glycerol-3-phosphate dehydrogenase (G3PDH) activity …
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Role of SMAD2 and SMAD3 on Adipose Tissue Development and Function
… diet-induced adiposity and to establish whether preadipocytes isolated from subcutaneous and visceral white adipose tissues differ in their differentiation capacity. We also assessed the role of activins on cell proliferation and differentiation using an in vitro model.</p> <p><strong>Research …
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Modulating adipogenesis via signaling pathways and cellular redox state
… cell physiology of human progenitor fat cells (preadipocytes). NO significantly promoted the differentiation process from immature fat cells to mature adipocytes. The proliferation of preadipocytes, however, was inhibited. The results of this thesis are especially helpful in the context of soft …
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Quantitation, Distribution and Secretion of Plasma Phospholipid Transfer Protein
Secretion of PLTP by mouse 3T3-L1 preadipocytes was also investigated. Characteristics of mouse adipocyte-secreted PLTP were similar to those of human plasma PLTP. Secretion of mouse PC transfer activity increased after differentiation.
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Identification of ITGBL1: A Novel Regulator of Adipogenesis
… up to this point has shown that the presumptive preadipocytes resemble pericytes: mesenchymal cells embedded in the vascular basement membrane (1). The pericyte is defined by this anatomic location as well as by the expression of the cell-surface marker platelet-derived growth factor receptor β …
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Tierexperimentelle Untersuchungen zur Adipogenese in Gel-Trägern als Weichgewebsersatz
… basis of biocompatible materials and autologous preadipocytes. Three different biomaterials (matrigel, collagen g , HYADD-3) were examined regarding their potency to induce adipose tissue. All three gels were implanted in a standardised chamber made out of acetal polymer into immune deficient …
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Cellular and Molecular Mechanisms Governing Intramuscular Fat Development and Growth in Cattle
… stage of adipose progenitor cells, and origin of preadipocytes. In addition, I tested the hypothesis that the delayed development and slower growth of IMF is in part due to inhibition by signaling proteins secreted by the surrounding muscle tissue. I conducted four studies. In the first study, I …
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Study of the antioxidant, anti-inflammatory and anti-diabetic effects of extracts from Cotinus coggygria in models with experimental animals and cell cultures // Проучване на антиоксидантното,противовъзпалително и противодиабетно действие на екстракти от Cotinus coggygria в експериментални модели с опитни животни и клетъчни култури
… of C. coggygria on cell cultures: 3T3-L1 (murine preadipocytes) and J774A.1 (murine macrophages);5)treatment of male Wistar rats with three aqueous extract from the leaves and aqueous-ethanolic extract of wood in a model of subchronic toxicity (30 days); (6) Study of in vivo antioxidant properties …
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Role of appetite-regulating peptides in adipose physiology in broiler chicks
… preadipocyte proliferation and differentiation. Preadipocytes were treated with NPY and gene expression and cellular proliferation were evaluated. Cells were also treated with NPY during differentiation and harvested during the later stages. With increased gene expression of proliferation markers …
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Altered regulation of adipogenesis with respect to disease processes
… profile of differentiating 3T3-L1 mouse preadipocytes and identified over 200 transcripts whose expression was altered. Four of these genes namely ITM2A, IGFBP5, PTPRQ and WNT6 were selected for detailed investigation using the 3T3-L1 in-vitro adipogenesis model. Preliminary …
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The Identification of the MCHR-1 in J774A.1 Macrophages and The Effect of Melanin-concentrating Hormone on a 3T3-L1 Adipocyte-J774A.1 Macrophage Co-Culture
… that MCH signaling by developing 3T3-L1 preadipocytes elicits changes in gene expression of several immune regulatory genes (Cook, 2021). I hypothesize that signaling between immune cells and adipose tissue contributes to the negative health outcomes of the obese phenotype. Co-culturing …
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