Global ETD Search

Investigating the relationship between clock gene stability and the pace of the vertebrate segmentation clock

Wiedermann, GuyUniversity of Dundee2014

Somites are precursors of the vertebrae, ribs, and associated musculature and their formation relies on ordered and timely segmentation during early embryonic development. Somites form as they ‘pinch’ away from the pre-somitic mesoderm (PSM) with a species-specific periodicity, coinciding with …

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Novel Notch signalling dynamics within the molecular oscillator underlying vertebrate segmentation

Bailey, Charlotte Sophie LouiseUniversity of Dundee2015

… in the caudal end of the embryo termed the pre-somitic mesoderm (PSM). This periodicity is regulated by a molecular oscillator underlain by negative feedback loops termed the ‘segmentation clock,’ which manifests as a dynamic pattern of gene expression that sweeps the PSM in a caudo-rostral …

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Investigation into the Expression, Role and Regulation of the Myc Oncogene during vertebrate embryonic body axis elongation

Mastromina, IoannaUniversity of Dundee2017

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