Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 64 for “"pre-eclampsia"”.
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Inflammatory Mediators Associated with Pre-eclampsia
PURPOSE: Pre-eclampsia, a hypertensive disorder unique in pregnancy, complicates approximately 5-7 % of pregnancies and is a leading cause of intrauterine fetal growth retardation, premature delivery, and maternal death. It is characterized by proteinuria, edema, platelet aggregation, and increased …
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Gestational hypertension - common pathways with pre-eclampsia
abstract is not provided.
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The role of nitric oxide in pre-eclampsia
Hypertension complicates approximately 10% of all pregnancies and is a leading cause of maternal and foetal mortality and morbidity world-wide. Pre-eclampsia is a major subgroup of these hypertensive disorders. It is defined as a rise in blood pressure to 140/90mm Hg or greater accompanied by …
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Vascular biology in the menstrual cycle, pregnancy and pre-eclampsia
… causes of maternal death in the United Kingdom. Pre-eclampsia is associated with increase in immediate and lifetime risk of adverse thrombotic events. Both pregnancy and the follicular phase are associated with arterial thrombosis and myocardial infarction. Modulation of haemostatic mechanisms in …
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Markers and mechanisms of pre-eclampsia in pregnancies complicated by diabetes
Pre-eclampsia complicates 2-8% of pregnancies worldwide. Women with diabetes have a 4-fold increased risk of pre-eclampsia compared to the general population. Mechanisms for pre-eclampsia development are not well understood; however, evidence indicates that an increased release of two …
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The role of heparin and heparin-binding growth factors in pre-eclampsia
… aims of this study tested the hypothesis that expression of heparin-binding growth factors (HBGFs) in normal placental development was altered in a specific pregnancy disorder preeclampsia. HBGFs bind to heparin, a glycosaminoglycan (GAG) affecting activity. I investigated the role of heparin and …
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Evaluation of selected South African medicinal plants in the treatment of pre-eclampsia
Submitted in fulfilment of the academic requirements for the degree of Doctor of Philosophy in Health Sciences at Durban University of Technology, Durban, South Africa, 2023.
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Role of kinins in mediating vascular function in healthy pregnancy and pre-eclampsia
Pre-eclampsia is a pregnancy-related disorder characterised by high blood pressure, proteinuria and oedema. The aetiology of the disease is unclear but evidence suggests that endothelial dysfunction is central to the development of the maternal syndrome. Kinins are endogenous peptides released by …
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CD146 expression in early and late onset pre-eclampsia : is there a difference?
Objective: To investigate the difference in expression of CD146 immunohistochemical staining on intermediate trophoblast in early and late onset pre-eclampsia placentas as well as comparing this expression to gestational age matched control placentas. Study Design: Retrospective case series of 100 …
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A study of vascular reactivity in women with pre-eclampsia using laser doppler fluximetry
Pre-eclampsia (PE) and eclampsia are severe complications of pregnancy of unknown aetiology. Laser Doppler fluximetry, a novel in-vivo technique, was used to assess cutaneous vascular reactivity in normotensive and pre-eclamptic women throughout pregnancy. The veno-arteriolar reflex was used as an …
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Urinary tract infection and pre-eclampsia in pregnancy : incidence of urinary tract infection in pre-eclamptic
… have found a positive association between UTI in pregnancy and the development of PET yet other studies have not found any such association. The objective is to determine the incidence of UTI in PET patients and thus determine if there is an assocition between UTI and PET.
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Clinical utility of 3D power doppler ultrasound and maternal biomarkers in the prediction of pre-eclampsia in high-risk pregnancies
Globally, pre-eclampsia is a leading cause of maternal and fetal morbidity and mortality. Approximately 2% of all pregnant women develop pre-eclampsia; women with high-risk co-morbidities are particularly at risk with reported incidences of up to 20%. Evolving evidence suggests that an integrated …
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Factors associated with pre-eclampsia and quality care of affected teenagers during labour within health region H. in KwaZulu-Natal Province
… identifying the factors that are associated with pre-eclampsia in teenagers. The study also aimed at assessing the quality of midwifery care during labour in teenagers with pre-eclampsia so that recommendations can be made based on empirical findings. The study was done within Health Region H of …
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Examining The Role Of Angiogenic Factors And Early Developmental Defects In The Pathogenesis Of Pre-Eclampsia In A Mouse Model, Bph/5
Pre-eclampsia (PE) is a devastating condition that affects 5-8% of pregnant women and is the leading cause of fetal and maternal deaths worldwide. The etiology of this disorder, however, is largely unknown. The BPH/5 mouse model is the only known rodent model that spontaneously develops the …
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Placental growth factor; potential for its use in twin pregnancy and evaluation of its benefit in singletons with suspected preterm pre-eclampsia
Hypertensive Disorders of Pregnancy are common and may result in increased maternal and neonatal morbidity and mortality. Twin pregnancies confer an increased risk of development of a hypertensive disorder of pregnancy. Placental growth factor is an angiogenic protein highly expressed during …
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The effect of calcium intake on body weight in pregnant women from South Africa, Zimbabwe and Argentina participating in the Calcium and Pre-eclampsia trial
Introduction: The prevalence of overweight and obesity is increasing worldwide. It has been estimated that every kilogram of weight gain during adulthood represents a 3% to 6% risk increased of cardiovascular disease. There are some studies showing an inverse relationship between calcium intake and …
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Maternal Haemoglobin and outcome of pregnancy
… haemoglobin concentration and the outcome of pregnancy has been a source of continual controversy. Preterm delivery and low birth weight are major causes of stillbirths and early neonatal deaths. Pre-eclampsia is a major complication which occurs during pregnancy and leads to significant …
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Exploration of how a mobile health (mHealth) intervention may support midwives in the management and referral of women with pre-eclampsia in rural and remote areas of highland Scotland.
… support midwives in the early identification of pregnancy complications in rural and remote locations. The purpose of this thesis was to undertake a qualitative and descriptive investigation into whether an mHealth intervention might be acceptable and useful to rural midwives in detecting and …
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A comparison of calcium levels in pre-eclamptic and normotensive pregnancies in a low dietary calcium setting
Pre-eclampsia is a leading cause of maternal mortality and morbidity in South Africa. At present this disease cannot be prevented and many interventions to reduce the incidence of pre-eclampsia have been investigated. Calcium supplementation of pregnant women at high risk of developing …
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Hemaglobinopathy and Pregnancy Outcomes: A Historical Cohort Study
Pregnancy in women with hemoglobinopathy has been associated with an increased risk of adverse pregnancy outcomes. We conducted a historical cohort study using Discharge Abstract Database for the fiscal year 1991-1992 through 2007-2008. We estimated the frequency of pregnant women with …
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