Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"postural instability"”.
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BIOMECHANICAL MARKERS AS INDICATORS OF POSTURAL INSTABILITY PROGRESSION IN PARKINSON'S DISEASE
… quantitative biomechanical parameters of postural instability in patients with Parkinson’s disease (PD) that can in turn be used to assess fall risk. Currently, clinical assessments in PD are not sufficiently sensitive to predict fall risk, making a history of falls to be the best …
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Cognitive and Behavioral Predictors of Fall Risk in Parkinson Disease
… stepwise logistic regression was significant for postural instability (odds ratio = 8.66), verbal learning (California Verbal Learning Test-2 Total Learning T Score [CVLT-II]) (odds ratio = 0.95), and self-reported behavioral impulsiveness (Barratt Impulsiveness Scale-11 [BIS-11]) (odds ratio = …
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Cognitive and Behavioral Predictors of Fall Risk in Parkinson Disease
… stepwise logistic regression was significant for postural instability (odds ratio = 8.66), verbal learning (California Verbal Learning Test-2 Total Learning T Score [CVLT-II]) (odds ratio = 0.95), and self-reported behavioral impulsiveness (Barratt Impulsiveness Scale-11 [BIS-11]) (odds ratio = …
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Human readaptation to normal gravity following short-term simulated Martian gravity exposure and the effectiveness of countermeasures
Postural instability is a main problem astronauts face upon return to Earth following space flights. The causes of postural instability include orthostatic intolerance, modified vestibular functions, and altered muscle gains. This thesis investigates the modifications in human walking gait …
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Predicting the vibration discomfort of standing passengers in transport
… experiment investigated the extent to which postural supports used by standing<br/>train passengers (vertical bar, shoulder support, and back support) affect discomfort caused<br/>by fore-and-aft and lateral vibration in the range 0.5 to 16 Hz. Supports that created a<br/>new path for the …
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Perturbation-based detection and prosthetic correction of vestibulopathic gait
… In order to prevent fall-related injuries due to postural instability, it is important to create both diagnosis techniques so that therapy can be applied before a fall occurs and devices which can aid the balance-impaired population. The aims of this research are twofold: 1) to develop metrics …
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The Use of Computerized Dynamic Posturography to Assess the Balance in Individuals with Parkinson's Disease
Postural instability is one of the hallmarks of Parkinson's disease (PD), currently evaluated using several subjective tools. However, the nature and degree of the resulting balance deficit is not well specified by these tools. Computerized dynamic posturography (CDP) provides an objective …
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Effects of Head Motion on Postural Stability in Participants with Chronic Motion Sensitivity
… Motion-provoked dizziness often causes postural instability. Purposes: This study aimed to compare the effects of head motion on postural stability in healthy adults with and without chronic motion sensitivity (CMS) and to determine the effects of head motion direction (horizontal versus …
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Modeling intrinsically disordered proteins ; a comprehensive study of [alpha]-synuclein
… resting tremors, rigidity, bradykinesia and postural instability - and pathologically by intraneuronal inclusions in the substantia nigra. Several studies suggest that a-synuclein, the major component of these intracellular inclusions, plays a major role in the neurodegenerative process. …
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Effect of Vestibular Adaptation Exercises on Chronic Motion Sensitivity
… vestibular dysfunction and typically impacts postural stability. Motion sickness, or motion sensitivity, is stimulated by abnormal spatial orientation and is a common symptom related to dizziness and postural instability. The main cause of the motion sensitivity is aberrant sensory input from …
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Quantifying Parkinson's Disease Symptoms Using Mobile Devices
… tasks. Assessments for tremor, bradykinesia, and postural instability are implemented to mimic UPDRS evaluations normally performed by a neurologist. The application connects to a cloud-based server to transfer the collected data for remote access and analysis. Example MatLab analysis demonstrates …
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Towards a quantitative assessment of early-stage Parkinson’s disease using BioVRSea paradigm
… motor functions characterize PD, and deficits in postural control are commonly seen. Currently, there is no cure for PD, and treatment options mainly focus on managing patients symptoms. The disease progresses over time, and the severity of symptoms increases, causing increasing disability and …
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Progress Towards Development Of Multifunctional, Dopamine D2/d3 Receptor Agonists As Symptomatic And Disease-Modifying Therapeutic Agents For Parkinson's Disease
… and decreased amplitude of movement), along with postural instability and cognitive psychiatric complications. PD affects 1% of the population ¡Ý 65 and is the second most prevalent neurodegenerative disorder next to Alzheimer¡¯s disease (AD). Although the etiology of PD is not yet clear and may …
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Postural Time-To-Contact, Real-Time Visual Feedback Of Postural Activity, And Motion Sickness
The postural instability theory of motion sickness predicts that the subjective symptoms of motion sickness will be preceded by unstable control of posture. In previous research, it has been confirmed with measures of the spatial magnitude and temporal dynamic of postural activity. In the first …
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Effects of Localized Muscle Fatigue on Postural Control: Interactive Effects with Inclined Surfaces and Unexpected Loads, and Intervention Efficacy
… factor that has been linked to a decrement in postural control and a potential increased falling risk. However, potential interactive effects of muscle fatigue with other risk factors remain unclear, and practical interventions are needed to mitigate the adverse effects of muscle fatigue. The …
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Surprising Behavioral and Neurochemical Enhancements in Mice with Combined Mutations Linked to Parkinson's Disease
… such as bradykinesia, tremor, rigidity and postural instability. Although most forms of the disease are spontaneous, a subset of cases are genetic and humans lacking expression of either Parkin or DJ-1 develop PD. However, one limitation to studying PD is a lack of rodent models that …
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Evaluation of Linear and Nonlinear Postural Stability Measurements Following Concussion
… A large number of these athletes suffer from postural instability following concussion. Postural control assessment has become a recommended tool to determine readiness to return to play. Measurement of postural control through the use of center of pressure (CoP) variables may provide a …
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The localization of UCH-L1(Ubiquitin C-terminaHydrolase-L1) in lipid rafts of neuronal cell
… Symtoms of PD are resting tremor, rigidity, postural instability and slowness of movement. Lipid rafts enriched glycosylphosphatidylinositol (GPI)-anchored proteins, glycosphingolipid and cholresterol, are specialized microdomains that play a role in endocytosis, exocytosis, signal …
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Rehabilitation Engineering in Parkinson's disease
Impairment of postural control is a common consequence of Parkinson's disease (PD) that becomes more and more critical with the progression of the disease, in spite of the available medications. Postural instability is one of the most disabling features of PD and induces difficulties with postural …
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Understanding Mediolateral Stability During Gait in Persons with Early-Stage Multiple Sclerosis
… disease that may contribute to the experience of postural instability, using of both commonly used and novel testing techniques for the MS population. Methods: Three individuals with early stage MS (MS1 = female aged 25, MS2 = female aged 33, MS3 = female aged 23) were included in this study and …
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