Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"postnatal growth"”.
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The effect of prenatal androgen exposure on sexual differentiation and postnatal growth in beef cattle
… genital structures; no studies have reported on postnatal growth and development of androgenized offspring. In the present study, pregnant cows were treated with l 7α-methyl-testosterone (MET, 250 mg/d, sq) from day 40 through 60 of gestation to induce virilization of female fetuses. Control cows …
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Effects of prenatal androgen exposure on postnatal growth, estrous cyclicity and behavior in female beef cattle
… on the external genitalia, estrous cyclicity, postnatal growth, social dominance and sexual behavior of female beef cattle. Pregnant cows received 17a methyl-testosterone (250 mg/d, sq) on d 40 to 100 (group 1), 70 to 130 (group 2) or 100 to 160 (group 3) of gestation. Control cows (group 0) …
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Role of SH3 and Cysteine-Rich Domain 3 (STAC3) in Skeletal Muscle Development, Postnatal Growth and Contraction
… essential for skeletal muscle contraction and postnatal life in mice. In this dissertation project, I conducted two studies to further understand the role of STAC3 in skeletal muscle development, growth, and contraction. In the first study, I compared the contractile responses of hindlimb …
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Maternal rumen-protected methionine supplementation alters dairy calf development, postnatal growth, plasma biomarkers, and liver one-carbon metabolism
Many factors influence fetal growth and development throughout pregnancy. During this critical time maternal nutrition is one of the most important factors that can affect offspring health and performance. Methionine, besides being the first limiting amino, is an important precursor of antioxidants …
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Fetal programming in cattle: the effects of varying maternal protein intake in adolescent beef heifers on fetal and postnatal growth and development of the calf
… gestation influences the fetal development, postnatal growth pathways and metabolism and reproductive development of the offspring. Wide variation in pasture quality and quantity available for the cow herd throughout the breeding season and during gestation is common in extensive grass-fed …
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A functional analysis of growth hormone receptor promoter regions in swine
[EMBARGOED UNTIL 08/01/2026] Growth hormone (GH) and its receptor (GHR) play critical roles in regulating growth, development, and reproductive function in animals. GHR expression in the liver is critical for postnatal growth and is regulated by tissue-specific promoters. While promoter 1 (P1) is …
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The role of the PWWP domain in the DNA methyltransferase 3A targeting to the genome
… However, the D329A mutation causes dominant postnatal growth retardation in mice. At the molecular level, it results in aberrant progressive acquisition of DNA methylation across domains marked by H3K27me3 and bivalent chromatin in multiple adult tissues. These domains characteristically …
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Contribution à l’optimalisation du support nutritionnel et de la croissance des prématurés de très faible poids à la naissance
Postnatal growth restriction (PNGR) is a common finding during neonatal hospitalization in very low birth weight (VLBW) infants. Insufficient nutritional support during the first weeks of life is responsible of major cumulative protein and energy deficit that has been considered as malnutrition. …
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Regulation of protein metabolism in skeletal muscle of low-birth-weight neonatal pigs
… in mammals is characterized by high rates of growth, attributed to rapid myonuclear accretion and protein deposition in muscle. Low-birth-weight (LBWT) neonates experience restricted muscle development, which leads to impaired postnatal growth and metabolic disorders later in life. The overall …
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Early life origins of the insulin resistance syndrome in the aged guinea pig.
In human populations, perturbed growth in early life and ageing have been identified as risk factors for the development of Insulin resistance syndrome (IRS). The consequences of restricted prenatal growth on postnatal function have been investigated using numerous experimental models of …
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The role of mammalian target of rapamycin complex 1 in hepatic physiology and disease
… complex 1 (mTORC 1) coordinates nutrient and growth factor inputs with numerous downstream processes including protein translation, autophagy, metabolism and cell growth. We have found that inhibition of mTORC 1 with rapamycin treatment suppressed whole-body postnatal growth similar to reduced …
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Muscle Growth and Development in Intrauterine Growth Restricted Pigs
Intrauterine growth restriction causes impaired growth and development of mammalian fetus, and leads to long-term negative effect on postnatal growth. Among domestic animals, pigs exhibit the most severe naturally occurring IUGR and reduced postnatal muscle growth. The objectives of this research …
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Perinatal essential fatty acid deficiency in mice: effects on metabolism and behaviour
… fatty acids is important for foetal and postnatal growth and development. The overall aim of this thesis was to study short- and long-term effects of perinatal essential fatty acid deficiency in mice on metabolism and behaviour. An essential fatty acid deficient (EFAD) diet or a control …
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Paediatric asthma and wheeze: early life origins
Epidemiological evidence suggests poor fetal growth is associated with poor later respiratory health, including the important childhood disorders asthma and wheeze. Factors creating a suboptimal early environment may persistently alter the structure and function of the immune and respiratory …
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Metabolic phenotypes of infants with normal birth weight, small-for-gestational-age, or after maternal gestational diabetes mellitus
… and a control population from the Cambridge Baby Growth Study (CBGS). The CBGS, set up in 2001, is an ongoing longitudinal cohort aiming to examine the ante- and postnatal determinants of infant growth and body composition, including genetic and environmental factors. While SGA infants in CBGS …
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Recapitulation of Human Placental Insufficiency in a Novel Mouse Model :New Paradigm in Translational Research
… ligation (MUAL) reliably resulting in fetal growth restriction (FGR).Methods: At 18 days, timed mated C57BL/6J dams were divided into two groups: MUAL(n=18) ; and control-sham operated (n=18) with uterine horn fetal positions matched to each MUAL fetus. Pups were delivered on day 20, …
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Molecular Regulation of Maternal Hepatic Adaptations to Pregnancy
… change; the placenta exhibited striking overgrowth with increased ALP production; and the cecal microbiome showed alterations in the relative abundance of several bacterial subpopulations. Moreover, litters born from maternal hepatic Ascl1 null mutated dam experienced abnormal postnatal …
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The Role of Nutrition and Administration of Estrogen in Holstein Calf Growth, Development, and Adenogenesis
… fertile replacement heifers. Manipulating early postnatal growth and development through diet enables this practice to be successful. Puberty is greatly influenced by body weight (BW). Once heifers reach puberty, they become fertile and can achieve their reproductive potential. Growth can easily …
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Effects of Ractopamine and Muscle Fiber Number on Swine Growth Performance, Carcass Traits, and Meat Quality
… ELANCO Animal Health, Greenfield, IN) on swine growth performance, carcass traits, meat quality and if its response is influenced by varying muscle fiber number and birth weight. The swine industry is under increasing pressure to maximize efficiency, profitability, and lean meat production. …
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Effects of ractopamine and muscle fiber number on swine growth performance, carcass traits, and meat quality
… ELANCO Animal Health, Greenfield, IN) on swine growth performance, carcass traits, meat quality and if its response is influenced by varying muscle fiber number and birth weight. The swine industry is under increasing pressure to maximize efficiency, profitability, and lean meat production. …
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