Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"post-transcription"”.
-
Stochastic Modeling of Gene Expression and Post-transcriptional Regulation
… is to develop and analyze stochastic models of post-transcription regulation. The analytical solutions of the models proposed provide insight into the effects of different mechanisms of regulation and the role of small RNAs in fine-tunning the noise in gene expression. The results derived can …
-
Magnesium regulates transcription of the mgtA (magnesium transporter) gene in Salmonella enterica serovar typhimurium via prolyl-bond formation during translation of the mgtL leader ORF
… that it exists at several stages, including transcription, post-transcription and post-translation, in response to Mg2+availability. The <em>mgtA</em> mRNA has a 264-nucleotide 5’ leader that contains a 17 codon, proline-rich ORF, termed <em>mgtL,</em> whose translation has been proposed to …
-
Investigating Hybrid Cyclic/Linear and Linear Peptides as Vehicles for Nucleic Acid Delivery
… temporarily downregulate gene expression through post-transcription RNA interference or permanently knockdown a protein via creating a mismatch in DNA, respectively. Nucleic acids are anionic and hydrophilic molecule, which cannot enter the cell through passive diffusion and/or interaction with …
-
Fluid Flow Forces Regulate Fibrous Extracellular Matrix Protein Expression and Deposition Via A Rhoa/Rho Kinase Dependent Pathway During Atrioventricular Valve Development
… immunofluorescence and TEM) confirmed the post-transcription results, and also showed the distinct spatiotemporal expression patterns of various fibrotic ECM proteins. </p> <p> In chapter 3, by using the in vitro fluid flow bioreactor culture system, our data suggested fluid flow forces …
-
Involvement of Translationally controlled tumor protein in Tomato yellow spot virus infection
… that TCTP mRNA may be the target of the plant post transcription gene silencing mechanism, leading to the production of small interfering RNAs (siRNAs) by the cleavage of Dicer proteins and the siRNAs generated might regulate the expression of host endogenous genes involves in virus infection. …
-
Protein coding transcription and control of vsp gene expression in the protozoan parasite Giardia lamblia
… eukaryotic in its cell and molecular biology, transcription in G. lamblia demonstrates important differences from these processes in higher eukaryotes. α-amanitin is a relatively selective inhibitor of eukaryotic RNA Polymerase II (RNAP II), and is commonly used to study RNAP II transcription. …
-
Understanding the dynamics of rhythmic gene expression in mammalian cells
… of over a dozen core-clock genes forming transcription-translation feedback loops. The core-clock mechanism also drives the rhythmic expression of downstream genes called clock-controlled genes, which are thought to be important for driving rhythmic biochemical and physiological processes. …
-
Computational analysis and method development for high throughput transcriptomics and transcriptional regulatory inference in plants
… to its ability to provide in-depth insights into transcription and post-transcription mechanisms, RNA-seq has been extensively used in functional genetics and transcriptomics, system biology and developmental biology in animals, plants, diseases, etc. The aim of this project is to use mathematical …