Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 46 for “"post-implantation"”.
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Morphogenesis of the early post-implantation mouse embryo
… morphogenetic events that give rise to the early post-implantation mouse embryo (egg cylinder) have not been thoroughly studied and our knowledge is restricted to “snap-shot” descriptions of embryos recovered at different stages of implantation from the mother. A central feature of the egg …
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Identification of Effective Strategies to Promote Language in Deaf Children with Cochlear Implants
… centers. Deaf children were assessed prior to implantation and then followed for three years post-implantation. At each assessment, parent-child interactions were videotaped in an unstructured Free Play and structured Art Gallery task. All parent and child speech, vocalizations, and sign …
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Illuminating the Black Box: Defining and Modeling Peri-Implantation Human Embryogenesis
… the inaccessibility of human embryos during implantation has limited our understanding of these stages. In this Thesis, I interrogated multiple aspects of human peri-implantation development. Utilizing human embryos cultured through implantation in vitro, I first generated a single cell …
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A multi-lineage in vitro mouse embryo model derived exclusively from mouse embryonic stem cells
… been developed to recapitulate various events of post-implantation development. Using only mouse embryonic stem cells (ESCs), the gastruloid model has been demonstrated to mimic basic body axis formation and aspects of gastrulation, somitogenesis, cardiogenesis, and neurulation. However, it fails …
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Lowered reproduction efficiency as a correlated response to selection for increased post-weaning gain in laboratory mice
… efficiency in mice selected for increased post-weaning gain. Four experimental groups were established: (1) Group C, the two control lines; (2) Group S, the four selected lines; (3) Group CS, the F₁ progeny from the 4 control line X selected line crosses; (4) Group SS, the F₁ progeny from 6 …
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Investigating the consequences of chromosome abnormalities arising during pre-implantation development of the mouse
The majority of human pre-implantation embryos created through in vitro fertilization (IVF) are mosaic as they are constituted of a mixture of diploid and aneuploid cells. Chromosome abnormalities are widely believed to contribute towards the relatively low success rates of IVF treatment. …
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Fabrication of electroluminescent silicon diodes by plasma ion implantation
… diodes made from silicon subjected to plasma ion implantation. A silicon-compatible, electrically driven light source is desired to increase the speed and efficiency of short-range data transfer in the communications and computing industries. As it is an indirect band gap material, ordinary …
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Age-Related Hamster Mitochondrial Changes and Oocyte Changes Following Autologous Platelet Mitochondrial Microinjection
… rule out that there might not be improvement of post-implantation embryo development. Therefore, further study will focus on effect of autologous platelet mitochondrial microinjection on post-implantation embryo development.</p>
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Effects of Daily Oral Injections of Quercetin on Implanted Colon-25 Tumor Growth in Balb-C Mice
… with a significant lymphopenia at day 20 post-implantation, and (3) there was relatively little evidence of histological changes in the quercetin-treated tumor section which would indicate that the action(s) of quercetin is primarily at the subcellular level probably within the nuclei of …
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Spinal cord regression via collagen entubulation
(cont.) days) post-implantation. Histological and immunohistochemical analyses showed severe fibrous and glial scar formation in Groups I and III, less fibrous scarring in Group II and very little scar manifesting in Groups IV and V. A quantitative analysis of myelinated axons in the center of the …
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The role of inherited determinants and embryonic-extraembryonic cell interactions in models of mammalian embryogenesis
… development. The study of early mammalian post-implantation development is challenging due to a lack of accessibility to the embryo as it grows in the uterus. Recent work has focused on establishing models to study and manipulate developmental stages that are equivalent to post-implantation …
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Encryption on the air : non-Invasive security for implantable medical devices
… connectivity that enables remote monitoring and post-implantation adjustment. However, recent work has demonstrated that flawed security tempers these medical benefits. In particular, an understandable lack of cryptographic mechanisms results in the IMD disclosing private data and being unable to …
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The Experiences of Women Who Live with an Implantable Cardioverter-Defibrillator (lCD)
… Despite its established health benefits, lCD implantation is accompanied by psychological factors which merit research attention. This study investigated the experiences of women who live an lCD. The homogenous, purposeful sample consisted of 15 women who had an lCD that was implanted within …
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Mechanisms and dynamics of size regulation and lumen formation in mouse double embryos
… double-sized embryos achieve downsizing after implantation but before gastrulation ensues. However, the exact timing and cellular mechanisms that regulate the morphogenetic events during double embryos development are still elusive. Here, we present a detailed morphological staging of …
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Mouse Embryo Development in the Presence of Capsaicin
… significantly inhibited embryo development. Post implantation fetuses were treated in the dam with 0.3, 0.6, 1.5, and 3 μmoles capsaicin, and tested for developmental defeds. No significant differences were found between the capsaicin treated fetuses and the control fetuses. Female mice were …
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A Mechanical and Histological Study of Functionally Graded Hydroxyapatite Implant Coatings
… implants will be restored following shorter post-operative healing periods and patients will more quickly regain masticatory function resulting in the overall improvement of physical and mental health.<br /><br />This study focused on mechanical and histological analysis of HA-coated and …
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Protein and cell therapy for lecithin-cholesterol acyltransferase (LCAT) deficiency
… regimes. LCAT activity was measurable in plasma post-injection and the percentage of esterified cholesterol increased, while agarose gel electrophoresis confirmed a rise in HDL levels. In a second approach, I encapsulated the recombinant CHO cells in biocompatible and semipermeable …
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The Generation of a Candidate Axial Precursor in Three Dimensional Aggregates of Mouse Embryonic Stem Cells
… that can recreate the events of early post-implantation development, including axial elongation. Gastruloids are the first ESC-based model for axial elongation morphogenesis; this body of work characterises their development and identifies a candidate population of NMps within their …
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A biohybrid bridge between brain and machine: Development and application of a neural implant using iPSC-derived neuronal membranes
… internal inflammatory mechanism triggered upon implantation of foreign objects, is responsible for fibrotic encapsulation of implanted neural probes, leading to a gradual decline in device functionality due to the physical barrier it creates between electrodes and host tissue (at the …
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Optimizing registration of complex vascular geometries
… catheter intervention, such as stent implantation. Yet, these imaging modalities are not universally embraced; and thus, optimization of stent implantation and management of the adverse outcomes remain challenging. This is partially because full adoption of complex imaging awaits …
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