Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"post-conditioning"”.
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Isoflurane-induced post-conditioning in senescent hearts is attenuated by failure to activate reperfusion injury salvage kinase pathway
… 3 min before and 2 min after reperfusion (ISO postC). Rats were subjected to coronary occlusion for 30 min followed by 2 h of reperfusion. Western blot analysis was used to assess the phosphorylation of extracellular signal-regulated kinase (ERK1/2), Akt, and GSK3β 15 min after reperfusion. …
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Effect of Isoflurane Post-treatment on tPA-exaggerated Brain Injury in a Rat Ischemic Stroke Model
… injury, and their protective role in ischemic post-conditioning is crucial for reducing ischemia-related injury. The aim of this study was to assess the effect of isoflurane post-treatment on intracranial hemorrhage and cerebral infarction after tPA treatment for transient cerebral ischemia. …
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Adaptive Mechanisms of the Heart to Ischaemic Stress
… separate group, we sought to examine the role of post-conditioning as a potential therapeutic tool in a randomised controlled trial involving patients undergoing primary percutaneous revascularisation for acute myocardial infarction.<br/>Results<br/>We were able to demonstrate that the reduction …
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INVESTIGATING THE ROLE OF α6 and α4 CONTAINING NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS IN NICOTINE AND COCAINE CONDITIONED PLACE PREFERENCE TESTS IN MICE.
… subunit were used. For CPP: On day 1, pre-conditioning scores were recorded; Days 2-4 mice underwent conditioning, where they were randomly assigned to either the black or the white compartment paired with drug, and the opposite chamber paired with saline; Day 5 was a drug-free test day …
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Antidepressant-Like Effects of Ketamine on Fear Conditioning and Extinction
… events can be studied in animals using fear conditioning and extinction paradigms. Fear conditioning trains an animal to associate a neutral cue with an emotionally aversive experience, while extinction learning challenges this association by forming a new memory that identifies the cue as …
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Membrane Stabilizing Copolymer Poloxamer 188 in Preclinical Models of Acute Myocardial Infarction Reperfusion
… reperfusion injury including ischemic pre-and post-conditioning, and therapeutic hypothermia have been successful in animal studies but have exhibited mixed results in clinical trials. Several cellular events that occur in ischemia including calcium overload and reactive oxygen species (ROS) …
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Nesfatin-1 Regulation of Cardiovascular Functions in Zebrafish and HL-1 Cardiomyocytes
… pressure in rats. In rats, nesfatin-1 acts as a post-conditioning agent and elicits cardioprotection against ischemia-reperfusion injury. It also affects the contraction and relaxation of the heart in rats in a dose dependent manner. Nesfatin-1 is emerging as a regulator of cardiovascular …
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Long-term depression of nociception and pain in healthy volunteers
… series were applied before (Pre) and after (Post) conditioning LFS (1 Hz, 20 min) to the hand dorsum. In Control experiments with the same volunteers no LFS was applied, but stimulation was interrupted. LFS effect was examined by electrophysiological, psychophysical and brain imaging methods. …
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The role of death-associated protein kinase in endothelial apoptosis under fluid shear stress
… our study examined the time-dependent effects of conditioning cells with shear stress on apoptosis triggered by TNF&agr;, oxidative stress, and serum depletion; and the corresponding role of endothelial DAPK. Pre-conditioning cells with shear stress for 6 hours prior to apoptosis induction, …