Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"positive symptoms"”.
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Positive Symptoms of Schizophrenia and Suicide: A Systematic Review of Gender, Race/Ethnicity, and Premorbid IQ Variables
… As such, suicide is of clinical concern. Positive symptoms such as hallucinations and delusions may influence the risk of suicide among individuals diagnosed with schizophrenia, but additional research is necessary, as the limited literature on this topic is dated and includes …
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EFFECTS OF OPTOGENETIC ACTIVATION AND PHARMACOLOGICAL MODULATION OF DOPAMINE NEURONS
… treatments used for schizophrenia. The “positive” symptoms (e.g., hallucinations, paranoia, etc.) of schizophrenia may come from overexpression of dopamine in mesolimbic dopamine neurons. Positive symptoms can be produced in healthy volunteers treated with amphetamine, a psychostimulant …
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An Examination of Clinical High-Risk Status, Sleep Quality, and Verbal Memory in a Community Sample Enriched for Psychosis Risk
… disturbances are associated with heightened CHR symptoms over time. Sleep is also vital for neural plasticity and other processes relating to human functioning. Verbal episodic memory is highly susceptible to sleep loss and is also notable for its discriminative utility in predicting likelihood …
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Enhanced striatal glutamatergic function upon chronic antipsychotic action
… disorder characterized by multiple clusters of symptoms including positive symptoms, such as hallucinations and delusions, negative symptoms, such as decreased motivation and flattened affect, and cognitive symptoms, such as memory impairment and impaired executive function. Currently available …
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Teaching Mindfulness to Individuals with Schizophrenia
… intervention has mitigated psychopathological symptoms and improved aspects of quality of life for many individuals. Studies of mindfulness-based training interventions for individuals with Schizophrenia disorders have been limited. These have targeted psychosis only or addressed anxiety …
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Teaching Mindfulness to Individuals with Schizophrenia
… intervention has mitigated psychopathological symptoms and improved aspects of quality of life for many individuals. Studies of mindfulness-based training interventions for individuals with Schizophrenia disorders have been limited. These have targeted psychosis only or addressed anxiety …
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Towards a mechanistic understanding of the neurobiological mechanisms underlying psychosis
Psychotic symptoms are prevalent in a wide variety of psychiatric and neurological disorders. Yet, despite decades of research, the neurobiological mechanisms via which these symptoms come to manifest themselves remain to be elucidated. I argue in this thesis that using a mechanistic approach …
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EXPERIENTIAL NEGATIVE SYMPTOMS IN YOUNG ADULTS ENDORSING PSYCHOTIC-LIKE EXPERIENCES
… studies of risk factors for psychosis focus on positive symptoms, such as subthreshold levels of hallucinations and delusions, fewer studies have examined negative symptoms in the early course of the schizophrenia or other psychotic disorders. This relative lack of focus on the role of negative …
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Introspective accuracy for social cognition across the psychosis spectrum: Influence of sleep disturbance
… one’s own abilities). Research suggests that positive, negative, and depressive symptoms may be related to IA, but findings are mixed. Examining sleep disturbance as a determinant of IA may help explain these mixed findings. The current study aimed to explore the relationships between sleep …
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Neural Indicator of Altered Mismatch Detection Predicts Atypical Cognitive-Perceptual Experiences in Psychotic Psychopathology
… BP, and SREL and was associated with greater positive symptoms of psychosis as well as self-reported atypical cognitive-perceptual experiences. Conclusions: Attentional modulation of early N1, and later P3 neural responses was atypical in patients, but the degree of attentional modulation did …
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Contributions of Sleep Quality and Dissociation to Attenuated Positive Psychotic Symptom Severity
… a link between sleep disturbance and worsened positive symptoms in CHR individuals. However, sleep disturbance is not unique to the psychosis-spectrum and is well documented in individuals experiencing dissociation. Transdiagnostically, dissociation has been associated with poorer outcomes and …
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An Investigation Into The Neural Nature Of Persecutory Ideation
… consistently associated with delusions or positive symptoms in order to aid development of a model of persecutory ideation and stimulate research. Brain regions highlighted by the review represented a convergence of neurobiological models of delusions, and were the focus of two empirical …
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Investigating the relationship between negative symptoms, autobiographical memory and concept of self in people recovering from first episode psychosis
… proportion of people who experience FEP display symptoms indicative of PTSD, it seems plausible that current theories derived from PTSD research may be useful in explaining some of the mechanisms involved in FEP. The study initially explored the idea that negative symptoms of psychosis are a …
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A qualitative analysis of the negative symptoms of schizophrenia interfering with academic and social success, and the exacerbators and diminishers of those symptoms.
… for schizophrenia are controlling the positive symptoms of hallucinations, illusions, and the severest of delusions, thus enabling these students to remain in school. However, many interfering negative symptoms remain (e.g., loss of goals, loss of former interests, cognitive …
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Cannabinoids and Psychosis – Cause and Treatment
… of THC can elicit transient psychotic symptoms and cognitive impairment. THC stimulates the endocanabinoid CB1 receptor (CB1R). However, beyond CB1Rs, the mechanism underlying the pro-psychotic effects of THC is unknown. <em>The ecploration of candidate mechanisms was the first major …
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Neurofunctional Characterization of the At-Risk Mental State for Psychosis
… psychiatric illness characterized by positive symptoms like hallucinations and delusions and negative symptoms like blunting of affect, avolition, and poverty of thought. This constellation of symptoms is hypothesized to result from dopaminergic dysfunction, glutamatergic dysfunction, …
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Investigating cortical arousal and cognition in schizophrenia and methamphetamine-induced psychotic disorder: an electroencephalography and cytokine study
… (MPD), are psychotic disorders characterized by positive symptoms (e.g., hallucinations and delusions), negative symptoms (e.g., social withdrawal, apathy), and impaired cognitive function. Despite the overlap in the clinical presentation of SCZ and MPD, no studies have compared …
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Effects of perinatal phencyclidine treatment on neuronal viability, N-methyl-D-aspartate receptor regulation and schizophrenic-like behaviors
… in humans has also been shown to mimic both the positive and negative symptoms of schizophrenia as well as exacerbate psychoses in schizophrenics. PCP elicits its major actions as a noncompetitive NMDA receptor (NMDAR) antagonist. Administration to immature rats has been shown to cause …
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EFFECTS OF REPEATED ARIPIPRAZOLE TREATMENT ON THE cAMP AND AKT PATHWAYS IN THE DORSAL STRIATUM OF PREADOLESCENT AND ADULT RATS
<p>The positive symptoms of schizophrenia primarily result from an excess of high affinity D2-like receptors (i.e. D2<sup>High</sup> receptors). First-generation antipsychotics, such as haloperidol, are D2-like antagonists that can cause severe extrapyramidal effects. Aripiprazole, a dopamine and …
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Experiences of Everyday Occupation among People with Psychiatric Disabilities - Relationships to social interaction, the worker role and day centre attendance
… person. Cohabitating and having a high level of positive subjective experiences of occupation were predictors of the quantity of social interaction. Having a high level of self-mastery, a low level of depression and fewer positive symptoms as well as being more satisfied with daily occupation …
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