Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"population balance models"”.
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Finite element and population balance models for food-freezing processes
… manufacturing. This thesis presents a series of models to address these issues. The first step taken to model energy consumption was to create a temperature-dependent ice cream material using empirical properties available in the literature. The homogeneous ice cream material is validated using …
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Mathematical modeling, simulation, and optimal design of pharmaceutical crystallizers
… a partial differential equation known as the population balance equation. This thesis constructs population balance models for three distinct particulate processes: 1) the breakage of crystals due to ultrasonication, 2) a semi-batch anti-solvent crystallization, and 3) continuous slug-flow …
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Dynamic modeling and analysis of oscillatory bioreactors
… problem. The complexity of first principle models also make model validation and analysis very difficult and model-based controller design practically intractable. This thesis has focused on finding an effective tool for model dynamic analysis, construction of low-dimension model and simple …
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Design and Analysis of Methods to Eliminate Oscillatory Behavior in Bioreactors for Viral Vaccine Manufacturing
… Finally, as an extension to these ideas, population balance models were analyzed to allow the tracking of individual populations of cells within a reactor - particularly those of a certain age group. As cells age, they may become less productive or more likely to exhibit genetic …
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Kinetic modeling of amyloid fibrillation and synaptic plasticity as memory loss and formation mechanisms
… data in vitro are available, few mechanistic models have been developed. To bridge this gap we used chemical engineering concepts from polymer dynamics, particle mechanics and population balance models to develop a mathematical formulation of amyloid growth dynamics. A three-stage mechanism …
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Kinetic modeling frameworks for the chemical recycling of polyolefins
… mechanism to build a continuous feature x population balance models (PBMs) that resolve the realistic molecular weight distribution (MWD) while keeping track of the evolution of functional motifs such as double bonds or end groups with a feature balance framework (FBM). We show how FBMs can …
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Breakup and coalescence in turbulent two-phase flows
… and coalescence in turbulent two phase flows. Models that can be used to simulate changes in a dispersion over time have been proposed, but these models contain constants that change with experimental conditions and empirical equations that can only be considered valid for certain experimental …
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Modeling and Control of Batch Pulsed Top-spray Fluidized bed Granulation
… was carried out including experimental study, population balance model (PBM), computational fluid dynamic (CFD) study and control strategy development. For the experimental study, the influence variables of pulsed frequency, binder spray rate and atomization pressure of a batch top-spray …
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Stochastic modelling of silicon nanoparticle synthesis
… simulate the formation of silicon nanoparticles. Population balance modelling is used to model nanoparticle synthesis and a stochastic numerical method is used to solve the governing equations. The population balance models are coupled to chemical kinetic models and offer insight into the …
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Multiscale models for polymer upcycling
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-15 without embargo terms
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Computational Modeling and Simulations of Hydrodynamics for Air-Water External Loop Airlift Reactors
… produced unstable solutions. Next, closure models for drag force and turbulent viscosity were investigated for a simple bubble column geometry. The effects of using a bubble pressure model and two drag coefficient models, the White model and the Schiller-Naumann model, were investigated. The …
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Scale-Up of Latex Reactors and Coagulators: A Combined CFD-PBE Approach
… distribution (PSD). The development of advanced population balance models (PBMs) has simplified this task at the laboratory scale, but commercialization remains challenging as it is difficult to maintain control over the composition (i.e. spatial distributions of reactant concentration) of larger …
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Mechanical dispersion of semi-solid binders in high-shear granulation
… and mechanical dispersion utilized experiments, population balance models, and discrete element method (DEM) models.</p> <p>The mechanical dispersion of the surfactant binder was studied using a lab scale 6 liter pin mixer. An experimental method was developed to isolate mechanical dispersion …