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Showing 1 to 1 of 1 for “"pontocerebellar hypoplasia type 1b"”.

  1. Identifying Subunit Organization and Function of The Nuclear Rna Exosome Machinery

    … subunit of the RNA exosome have been linked to pontocerebellar hypoplasia subtype 1b (PCH1b). My work has included the development of a laboratory model system to assess the specific effects of these mutations on the structure and function of the RNA exosome. My collaborators and I have employed …

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