Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 16 of 16 for “"polyunsaturated fatty acid (PUFA)"”.
-
An investigation of consumers’ decision processes and styles
… The new product in the current study was polyunsaturated fatty acid (PUFA) fed fish, a healthy food. Previous research has found attitude to determine purchase of food products (Shepherd and Farleigh 1986). Other research has found involvement and cognitive style to interact to predict the …
-
Regulation of n-3 PUFA biosynthesis in proliferating and differentiated PC12 pheochromocytoma cells
Regulation of polyunsaturated fatty acid (PUFA) biosynthesis in proliferating and NGF-differentiated PC12 pheochromocytoma cells deficient in n-3 docosahexaenoic acid (DHA, 22:6n- 3) was studied. A dose- and time dependent increase in eicosapentaenoic acid (EPA, 20:5n-3), docosapentaenoic acid …
-
The role of eicoapentaenoic acid in cancer cahexia
… β3-adrenoceptors. Oral administration of the n-3 polyunsaturated fatty acid (PUFA) eicosapentaenoic acid (EPA) attenuated the progression of cachexia, but not the production of LMF, in MAC16 tumour-bearing mice, and was significantly incorporated into plasma phospholipids, skeletal muscle and …
-
FADS2 expression modulates effect of dietary polyunsaturated fatty acids on western diet-induced glucose intolerance
Fatty Acid Desaturase 2 (FADS2) haplotypes associated with hyperactivity of its gene product, delta-6-desaturase (D6D), are associated with obesity and type-2 diabetes in humans. D6D regulates long-chain polyunsaturated fatty acid (PUFA) biosynthesis and is upregulated in several rodent models of …
-
Identifying and dissecting novel QTL regulating seed fatty acid composition in Arabidopsis thaliana for the improvement of rapeseed oil
Genes encoding desaturases in the polyunsaturated fatty acid (PUFA) biochemical pathway have been identified by mutation analyses and utilized in oilseed rape (Brassica napus) breeding programs. However the regulation mechanisms of these genes are as yet unknown and pursued by the oil industry for …
-
Mechanism of Action of Pentobarbital Induced Attenuation of Vascular Smooth Muscle Contraction
… was increased by treatment with docosahexaenoic acid (22:6), a polyunsaturated fatty acid (PUFA), to compare the effects of PB (30 uM, 20 min). PUFA and/or PB treatment had no effect on transient ECI in resting cells over a range of temperatures (32, 34.5, 37, 39.5, 41°C). However, both PUFA …
-
Functional Analysis of Dehydratase Domains of a Polyunsaturated fatty acid Synthase from Thraustochytrium sp. by Mutagenesis
Very long chain polyunsaturated fatty acids (VLCPUFAs), such as docosahexaenoic acid (DHA, 22:6-4,7,10,13,16,19) and eicosapentaenoic acid (EPA, 20:5-5,8,11,14,17), are essential for humans and animals since they are parts of the cell membrane and are involved in mediating various physiological …
-
The effect of eicosapentaenoic acid on brain and platelet produced bioactive lipid mediators. The effect of eicosapentaenoic acid, docosapentaenoic acid and other polyunsaturated fatty acids on the eicosanoids and endocannabinoids produced by rat brain and human platelets using electrospray ionisation tandem mass spectrometry-based analysis.
Eicosapentaenoic acid (EPA) is a polyunsaturated fatty acid (PUFA) with neuroprotective and cardioprotective properties. It is thought that some of the actions of EPA may be attributed to its elongated metabolite, the PUFA docosapentaenoic acid (DPA). Docosahexaenoic acid (DHA) and arachidonic acid …
-
Dietary long-chain polyunsaturated fatty acids affect plasma and tissue lipids in chickens
… how dietary lipid sources influence lipid and polyunsaturated fatty acid (PUFA) metabolism when fed to young, growing chickens. In the first experiment, commercial meat-type chickens were fed one of four dietary lipids: 1) linseed oil (LO); 2) menhaden oil (MO); 3) soybean oil (SBO); or 4) …
-
Polyunsaturated fatty acid requirements of murine colon adenocarcinomas
The polyunsaturated fatty acid (PUFA) requirements of three transplantable murine colon adenocarcinomas, the MAC13, MAC16 and MAC26, were evaluated in vitro and in vivo. When serum concentrations became growth limiting in vitro, proliferation of the MAC13 and MAC26 cell lines was stimulated by …
-
INVESTIGATION OF THE CARDIOPROTECTIVE AND HYPOTRIGLYCERIDEMIC POTENTIAL OF ECHIUM OIL AS A BOTANICAL SOURCE OF LONG CHAIN N-3 FATTY ACIDS
… response. Consumption of fish oil (FO) and n-3 polyunsaturated fatty acid (PUFA) supplements has been shown to be cardioprotective and result in several health benefits, including reduced plasma triglyceride (TG) concentration, inflammation, endothelial cell activation, and atherosclerosis. FO …
-
Antibacterial activity of polyunsaturated fatty acids related to chronic wound infections
… toleranceor resistance to antimicrobials. The polyunsaturated fatty acid (PUFA) compounds includingDocosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) offer bothimmunomodulatory and antimicrobial properties that could enhance wound healing. This study evaluated the activity and …
-
OMICS APPROACHES FOR OMEGA-6/OMEGA-3 POLYUNSATURATED FATTY ACID RATIO IN PIGS
In general, meat quality is heavily influenced by fatty acid (FA) composition and intramuscular fat, which is mostly dependent on the dietary fat intake of pigs, but it is also affected by genetic variants. In this PhD thesis, we elucidated the effects of dietary lipids, in terms of omega-6 …
-
Effects of maturation, polyploidy, and nutrition on growth, composition, and gene expression within fatty acid metabolism in rainbow trout
… growth responses, fillet quality attributes, and fatty acid content. Additionally, changes in gene expression of 35 genes within the regulatory pathways governing fatty acid metabolism of various energy stores were investigated to elucidate mechanisms regulating nutrient repartitioning during …
-
Cytochrome P450 2J2 mediated metabolism of omega-6 and omega-3 endocannabinoids
… and brain where it mediates the metabolism of polyunsaturated fatty acids into oxygenated bioactive metabolites. This enzyme is most well-known for the conversion of arachidonic acid into epoxyeicosatrienoic acids (EETs) regioisomers, 14,15-, 11,12-, 8,9-, and 5,6-EET that mediate vasodilatory, …
-
Impact of Epa and Dha Supplementation and 15-Lox-1 Expression On Colitis and Colitis-Associated Colorectal Cancer
… (15-LOX-1) is crucial to converting omega-3 fatty acid derivatives eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to resolvins, potent anti-inflammatory products. 15-LOX-1 effects on the conversion of EPA and DHA to resolvins that subsequently exert anti-inflammatory and …