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Showing 1 to 20 of 269 for “"polyunsaturated"”.
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Polyunsaturated fatty acids and immune cell functions
In MS patients there was a significantly positive relationship between membrane AA and TGF-ß1 indicating that it is the individual long chain (LC) PUFA, i.e. AA that regulate the levels of TGF-ß1. Investigation of the effects of n-6 and n-3 PUFAs on normal healthy PBMC production of TGF-ß1 in vitro …
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Polyunsaturated fatty acid requirements of murine colon adenocarcinomas
The polyunsaturated fatty acid (PUFA) requirements of three transplantable murine colon adenocarcinomas, the MAC13, MAC16 and MAC26, were evaluated in vitro and in vivo. When serum concentrations became growth limiting in vitro, proliferation of the MAC13 and MAC26 cell lines was stimulated by …
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Rumen biohydrogenation of polyunsaturated fatty acids in high quality pasture
The intake of polyunsaturated fatty acids, such as omega-3 fatty acids and conjugated linoleic acids, can prevent many diseases such as coronary heart disease, cancer, diabetes and hypertension. This work looked at aspects of the control of polyunsaturated fatty acid levels in milk. Pasture …
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A role for polyunsaturated fatty acids in Th1-mediated disease
The anti-inflammatory effects of polyunsaturated fatty acids (PUFA) have been well documented, however their exact method of action remains elusive. Dendritic cells (DC) are the most potent antigen presenting cell (APC) and we found that n-3 and n-6 PUFA suppressed IL-12p70 and enhanced IL-10 …
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Antibacterial activity of polyunsaturated fatty acids related to chronic wound infections
… toleranceor resistance to antimicrobials. The polyunsaturated fatty acid (PUFA) compounds includingDocosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) offer bothimmunomodulatory and antimicrobial properties that could enhance wound healing. This study evaluated the activity and …
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The dietary essentiality of n-3 polyunsaturated fatty acids in infant nutrition
Docosahexaenoic acid (22:6n-3) and arachidonic acid (20:4n-6) are deposited in large amounts in membrane phospholipids of the developing central nervous system (CNS). High levels of 22:6n-3 are found in synaptic terminals and retina, and are important for normal visual development and function. …
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Enhancing the production of Omega-3 polyunsaturated fatty acids in marine diatoms
The primary producers of essential omega-3 polyunsaturated fatty acids are marine microalgae, which form the base of the aquatic food web. One alternative source of our ever diminishing stocks of fish and fish oil is via the cultivation of these microorganisms. Unfortunately, these microalgae, of …
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OMICS APPROACHES FOR OMEGA-6/OMEGA-3 POLYUNSATURATED FATTY ACID RATIO IN PIGS
… lipids, in terms of omega-6 (n-6)/omega-3 (n-3) polyunsaturated fatty acid (PUFA) ratio, on porcine meat quality and the integration of OMICS technologies such as genomics, transcriptomics, and proteomics. With the aim of understanding the association between n-6/n-3 PUFA ratios, porcine …
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Computational studies on polyunsaturated fatty acid uptake and its effects on antimicrobial resistance
… has the ability to uptake and utilize long chain polyunsaturated fatty acids up to 22 carbon atoms long. Before this discovery was made, conventional belief was that fatty acids of greater than 18 carbons long were toxic to bacteria. Further investigations have revealed that this uptake is not …
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Solid-state NMR spectroscopy applied to model membranes: effects of polyunsaturated fatty acids
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) relieve the symptoms of a wide variety of chronic inflammatory disorders. Typically, they must be obtained in the diet from sources such as fish oils. Docosahexaenoic acid (DHA) is one of these n-3 PUFAs. As yet the structural mechanism responsible …
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Polyunsaturated fatty acids and inflammatory biomarkers in the pathogenesis of type II diabetes
Various studies have reported elevated levels of pro-inflammatory cytokines (IL-6, TNF-α, MCP-1, IL-1β) and different fatty acid (FA) patterns are associated with type 2 diabetes mellitus (DM2). In addition, an association of hypovitaminoses D with DM2 has been observed in some populations. No …
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Dietary long-chain polyunsaturated fatty acids affect plasma and tissue lipids in chickens
… how dietary lipid sources influence lipid and polyunsaturated fatty acid (PUFA) metabolism when fed to young, growing chickens. In the first experiment, commercial meat-type chickens were fed one of four dietary lipids: 1) linseed oil (LO); 2) menhaden oil (MO); 3) soybean oil (SBO); or 4) …
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Producing Omega-3 Polyunsaturated Fatty Acids from Biodiesel Waste Glycerol by Microalgae Fermentation
… which are prolific producers of omega-3 polyunsaturated fatty acids. Omega-3 fatty acids have many beneficially effects on treating human diseases such as cardiovascular diseases, cancers, and neurological disorders. In addition, the omega-3 fatty acids docosahexaenoic acid (DHA) has been …
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The effects of feed supplemented with omega-3 polyunsaturated fatty acids on cultured abalone
The long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) are associated with a broad range of health benefits including reducing the risk of cardiovascular diseases, arthritis and certain cancers. In addition, they have also been found to play a role in reducing the risk of Alzheimer’s …
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Regulation of glucose -6 -phosphate dehydrogenase by polyunsaturated fatty acids in cultured rat hepatocytes
… understand the molecular mechanism(s) by which polyunsaturated fatty acids inhibit gene expression of the lipogenic enzymes. The model enzyme which we are using to study this phenomenon is liver glucose-6-phosphate dehydrogenase (G6PD). In order to determine if regulation of G6PD occurred at a …
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Stress responses of the marine diatom <i>Skeletonema</i> spp. to polyunsaturated aldehydes (PUAS)
Diatom-derived polyunsaturated aldehydes (PUAs) are secondary metabolites acting as teratogens against grazers, allelochemicals by inhibiting the growth of closeby phytoplankton species, and also as signal molecules to determine the cell fate of diatom populations. <br></br><br></br>The work …
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Microencapsulation of an omega-3 polyunsaturated fatty acid source with polysaccharides for food applications
Omega-3 polyunsaturated fatty acids (ω3 PUFAs) provide important health benefits, but dietary consumption is low. Supplementing foods with ω3 PUFAs is of interest, but intervention strategies are necessary to preserve the integrity of these unstable compounds. Microencapsulation of ω3 PUFA sources …
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FADS2 expression modulates effect of dietary polyunsaturated fatty acids on western diet-induced glucose intolerance
… diabetes in humans. D6D regulates long-chain polyunsaturated fatty acid (PUFA) biosynthesis and is upregulated in several rodent models of obesity/insulin resistance, but its direct influence on diabetes is unclear. D6D activity might favor pathogenic effects of omega-6 FA linoleic acid (LA) …
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