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Showing 1 to 20 of 21 for “"polyribosomes"”.
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Kh Domains on Brain Polyribosomes: FMRP and Nova in Translational Regulation
… in human disease are associated with brain polyribosomes, namely the Nova and Hu paraneoplastic antigens and the Fragile X mental retardation protein. We use microarray analysis of polyribosomal mRNAs in knockout mouse models of these diseases to identify target mRNAs and analyze the …
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Isolement et caractérisation du complexe polyribosomes-cytosquelette de cerveaux de hamster
Dans la cellule, les polyribosomes sont associés au cytosquelette pour former un complexe polyribosomes-cytosquelette. Jusqu'à maintenant, les données portant sur cette structure provenaient presque exclusivement de cultures de cellules transformées. En travaillant avec les cellules de cerveau de …
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Characteristics of Polyribosomes in Germinating Seeds and Growing Root Tip Tissue
Made available in DSpace on 2014-12-10T17:12:36Z (GMT). No. of bitstreams: 1 6808262.pdf: 4936198 bytes, checksum: 0da29fb00b1cb711ffeeed54bd5d1f1c (MD5) Previous issue date: 1967
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Quantitative and qualitative comparisons of polyribosomes from healthy and southern bean mosaic virus-infected Contender bean
Call number: LD2668 .T4 1978 R35
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Quantitative and qualitative comparisons of polyribosomes from healthy and southern bean mosaic virus-infected Contender bean
Call number: LD2668 .T4 1978 R35
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L' effet de la phénylcétonurie expérimentale sur la synthèse protéique chez les cellules de cerveau de hamsters
… a l'aide de profils de sedimentation des polyribosomes totaux bruts et des polyribosomes cytosquelettiques vs polyribosomes solubles. De plus, nous avons etudie l'effet de divers stress (chocs thermiques) sur le taux de synthese proteique. Ainsi, nous avons demontre que la synthese …
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Complementary DNA to sea urchin histone messenger RNA
… isolated from early blastula sea urchin embryo polyribosomes by phenol extraction followed by repeated sucrose density gradient centrifugation. When incubated in an ascites cell free protein synthesizing system this preparation of RNA was shown to support the synthesis of sea urchin histones …
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Mechanism of Translational Control by the Fragile X Mental Retardation Protein and Creation of the FMRP CTAG Mouse
… protein that is predominantly associated with polyribosomes. Loss of FMRP results in Fragile X Syndrome, characterized by mental retardation, autism and epilepsy. FMRP was recently found to be associated with a specific set of mRNAs with key roles in neuronal function and to physically interact …
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Morphological and histochemical observations of hepatic peroxisomes and lysosomes of rats after treatment with methylmercuric chloride, hydrogen peroxide and gamma radiation
… loss of mitochondrial cristae and presence of polyribosomes and/or glycogen were observed at day 2. Seepage of hydrolytic enzymes from disrupted lysosomal membrane and persistence of polyribosomes or glycogen and dissolution of mitochondrial cristae were observed at day 7. Diffusion of reaction …
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ΚΑΘΑΡΙΣΜΟΣ ΚΑΙ ΜΕΛΕΤΗ ΜΙΑΣ ΕΙΔΙΚΗΣ ΡΙΒΟΝΟΥΚΛΕΑΣΗΣ ΚΑΙ ΕΝΟΣ ΑΝΑΣΤΟΛΕΑ ΤΗΣ ΠΡΩΤΕΙΝΟΣΥΝΘΕΣΗΣ ΑΠΟ ΠΡΟΝΥΜΦΕΣ 6 ΗΜΕΡΩΝ ΤΟΥ ΕΝΤΟΜΟΥ CERATITIS CAPITATA
… THE ELONGATION OF NASCENT POLYPEPTIDE CHAINS OF POLYRIBOSOMES IS DEVELOPED ANDHS PROPERTIES TOGETHER WITH ITS ACTION IN IN VITRO SYSTEMS OF PROTEIN SYNTHESIS ARE STUDIED.
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Surface Functionalizations towards Nucleic Acid Purification: a nanoscale study
… mRNA, forming supramolecular complexes known as polyribosomes (polysomes).This project is aimed at developing and studying a miniaturized purification system able to isolate and extract polysome-associated mRNA, namely mRNA under active translation. The resulting microdevice will constitute a …
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Effects of stratification on in vitro protein synthesis using components from embryos of Pinus lambertiana Dougl.
… consisted primarily of monoribosomes but some polyribosomes were present in both dormant and stratified embryos. Analysis of incubation mixtures produced similar results. The majority of the labelled polyphenylalanine was associated with the monoribosomes.
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An Ultrastructural Survey of the Nuchal Glands of <i>Rhabdophis tigrinus</i> (Serpentes: Colubridae)
… low numbers of steroidogenic mitochondria, polyribosomes, and evidence of pinocytotic activity along nuchal gland cell membranes strongly suggests that the steroidogenic compounds in the gland product are derived from the diet and sequestered in the nuchal gland. The variable quality of …
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Genetic and biochemical analysis of the Drosophila melanogaster homolog of the human SCA2 gene
… that both proteins physically assemble with polyribosomes, thus indicating that these proteins function in cytoplasmic RNA metabolism. These results suggest that SCA2/Datx2 function to regulate RNAs encoding components of actin filament formation pathways. Further, these results raise the …
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The mechanisms regulating the transcription factor ATF5 and its function in the integrated stress response
… preferential association of ATF5 mRNA with large polyribosomes in response to stress. ATF5 translational control involves two upstream open reading frames (uORFs) located in the 5′-leader of the ATF5 mRNA, a feature shared with ATF4. Mutational analyses of the 5′-leader of ATF5 mRNA fused to a …
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Identification of Loss of Specific FMRP-RNA Interactions as a Cause of Fragile X Syndrome
… defective in RNA binding and is dissociated from polyribosomes. Moreover, electrophysiologic and behavioral deficits of the I304N mouse reveals that the mutation confers an FMRP-null-like phenotype on the mouse. These observations support the suggestion that a key function of FMRP in mediating …
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Microrna-mediated regulation and the fragile X family of proteins
… is found associated with stalled untranslating polyribosomes and translation of at least one mRNA is downregulated when FMRP is phosphorylated. We hypothesized that translational regulation by P-FMRP is accomplished through association with the miRNA pathway. Accordingly, we developed a …
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Finding Common Ground: The Common Marmoset as a Model to Accessing and Providing Insight into the Social Brain
… enables sequencing of mRNA bound to EGFP-tagged polyribosomes from chosen projection neurons that have been virally labeled with an EGFP-L10a transgene. retro-vTRAP facilitates the study of gene expression patterns in specific neural cell types to be studied in the complex, heterogeneous tissue …
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The Biogenesis of Peroxisomal Catalase in Rat Liver
… either from the synthetic activity of free polyribosomes, or from a homogenization artifact whereby a fragile particle is broken open.</p>
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