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Showing 1 to 3 of 3 for “"polyphosphate modification"”.
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Lysine Polyphosphate Modification Regulates Enzymatic and Signaling Functions in Eukaryotic and Bacterial Systems
Polyphosphate (polyP) is a highly conserved inorganic polymer involved in diverse regulatory processes across all domains of life. In bacteria, polyP is synthesized primarily by polyphosphate kinase 1 (PPK1) and deletion of the ppk1 gene results in significant alterations in cellular physiology and …
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Polyphosphate Modification of Human Proteins and a New Mechanism for Regulating Super-Enhancer Activity
Inorganic polyphosphate (polyP) is an evolutionarily conserved linear polymer of orthophosphate that plays diverse regulatory roles across biological systems. Recent work has implicated that polyP modulates protein function through post-translational modification (PTM), which has gained increasing …
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Investigating the polyphosphate interactome with lysine- and histidine-rich proteins
Inorganic polyphosphate (polyP) is a biomolecule whose diverse functionality greatly belies its simple structure. PolyP is comprised of repeated inorganic phosphate units forming high energy phosphoanhydride linked polymers. Numerous studies have highlighted its vast portfolio of functions that …