Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 99 for “"polyphosphate"”.
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Mechanisms of polyphosphate degradation
… to investigate the mechanisms by which inorganic polyphosphate (polyP) is degraded in vivo. PolyP is a linear chain of phosphate moieties linked through high-energy phosphoanhydride bonds and can range in size from three-phosphates-long to thousands. Naturally, these molecular chains are stored in …
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Quantifying polyphosphate energy for modelling of polyphosphate accumulating organisms behaviour in anaerobic digestors
This study investigated the behaviour of polyphosphate accumulating organisms (PAOs) in linked activated sludge-anaerobic digestion (AS-AD) systems, with particular focus on quantifying polyphosphate (PolyP) energy and its role in PAO metabolism. The study was motivated by observed discrepancies …
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Polyphosphate modulates hemostasis, thrombosis, and inflammation
Polyphosphate (polyP) is a linear polymer of inorganic phosphates that is secreted by activated platelets and is abundant in many pathogenic microorganisms. Our lab has recently shown that polyP from bacteria and human platelets play important roles in inflammation and coagulation in vitro and in …
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Pelleting performance as affected by ammonium polyphosphate
Typescript (Photocopy).
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Exploring Polyphosphate Biology Regulation in Saccharomyces cerevisiae
À la demande de l'auteur, le résumé a été retiré en raison de la nature confidentielle de la thèse. Il sera ajouté une fois la période d'embargo terminée. At the author’s request, the abstract has been removed due to the confidential nature of the thesis. It will be added once the embargo period …
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Investigating the polyphosphate interactome with lysine- and histidine-rich proteins
Inorganic polyphosphate (polyP) is a biomolecule whose diverse functionality greatly belies its simple structure. PolyP is comprised of repeated inorganic phosphate units forming high energy phosphoanhydride linked polymers. Numerous studies have highlighted its vast portfolio of functions that …
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Tilliage implement applications of anhydrous ammonia and liquid ammonium polyphosphate
Digitized by Kansas Correctional Industries
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Polyphosphate and tissue factor/factor VIIA as initiators of coagulation
… The roles of anionic polymers such as inorganic polyphosphate and nucleic acids in both coagulation and inflammation have recently come to light. To better understand and delineate their effects, I performed a head-to-head comparison of the abilities of polyphosphate, DNA, and RNA to activate the …
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STRUCTURE-FUNCTION STUDIES OF MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASES FROM GUT COMMENSAL BACTERIA
… have been found to produce multiple inositol polyphosphate phosphatases (Minpp) which display phytase activity. In this study, high resolution X-ray crystal structures of Minpps from two human commensal gut bacteria, Bacteroides thetaiotaomicron (BtMinpp) and Bifidobacterium longum (BlMinpp), …
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The role of polyphosphate kinase in long term survival of Helicobacter pylori
Thesis (S.M.)--Massachusetts Institute of Technology, Division of Bioengineering and Environmental Health, 1999.
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Identification and Functional Role of Myo-Inositol Polyphosphate 5-Phosphatase Protein Complexes
… second messenger hydrolysis. Myo-inositol polyphosphate 5-phosphatases (5PTases) (EC 3.1.3.56) have unique signal terminating abilities toward the second messenger inositol trisphosphate (Ins (1,4,5)P3, InsP3). In Arabidopsis thaliana there are 15 members of the 5PTase family, the majority …
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Lysine Polyphosphate Modification Regulates Enzymatic and Signaling Functions in Eukaryotic and Bacterial Systems
Polyphosphate (polyP) is a highly conserved inorganic polymer involved in diverse regulatory processes across all domains of life. In bacteria, polyP is synthesized primarily by polyphosphate kinase 1 (PPK1) and deletion of the ppk1 gene results in significant alterations in cellular physiology and …
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A study into the properties and applications of bacterial microcompartments and polyphosphate metabolism
… extracellular environment and the retention of polyphosphate intracellularly. This was observed experimentally through the engineering of recombinant constructs containing genes encoding microcompartment-directed polyphosphate kinase enzyme. Bacterial phenotypes conferred by these constructs …
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Polyphosphate Modification of Human Proteins and a New Mechanism for Regulating Super-Enhancer Activity
Inorganic polyphosphate (polyP) is an evolutionarily conserved linear polymer of orthophosphate that plays diverse regulatory roles across biological systems. Recent work has implicated that polyP modulates protein function through post-translational modification (PTM), which has gained increasing …
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Polyphosphate is a novel modulator of coagulation and inflammation and is a therapeutic target
… and thrombosis focuses on how inorganic polyphosphate (polyP) can mediate many of these novel amplification steps and many of the connections between coagulation and inflammation. Additionally, the multiple procoagulant and proinflammatory roles for polyP discovered in both mice and …
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The metabolic role of intracellular inorganic polyphosphate during the synchronous growth of Chlorella pyrenoidosa
… was to determine the relationship of inorganic polyphosphate to the total metabolism of phosphorus by C. pyranoidosa.
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Possible mechanisms controlling the intracellular level of inorganic polyphosphate during synchronous growth of chlorella pyrenoidosa
… intracellular levels of inorganic acid-insoluble polyphosphate, (Pi)x, during cellular growth and division.
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A Physiological, Biochemical and Structural Analysis of Inositol Polyphosphate 5-Phosphatases from Arabidopsis thaliana and Humans
… thaliana contains fifteen predicted inositol polyphosphate 5- phosphatases (5PTases, E.C. 3.1.3.36) that have the potential to remove a 5-phosphate from various inositol second messenger substrates. To examine the substrate specificity of one of these Arabidopsis thaliana 5PTases (At5PTases), …
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Growing an Enhanced Culture of Polyphosphate Accumulating Organisms using a University of Cape Town Membrane Bioreactor (UCTMBR) System
… plant (WWTP). This EBPR process utilizes polyphosphate accumulating organisms (PAOs), which can accumulate P as polyphosphate (a metal phosphate complex that requires much larger P quantities than the P used for nutritional purposes in the biomass anabolic process). The resulting P-rich …
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High-Yield Cellulosic Hydrogen Production by Cell-Free Synthetic Cascade Enzymes: Minimal Bacterial Cellulase Cocktail and Thermostable Polyphosphate Glucokinase
… fusca YX was hypothesized to have a thermophilic polyphosphate glucokinase. T. fusca YX ORF Tfu_1811 encoding a putative PPGK was cloned and the recombinant protein fused with a family 3 cellulose-binding module (CBM-PPGK) was over expressed in Escherichia coli. By a simple one-step …
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