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Showing 1 to 20 of 278 for “"polypeptides"”.
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Optical Rotatory Properties of Polypeptides
Made available in DSpace on 2014-12-09T17:36:32Z (GMT). No. of bitstreams: 1 7013276.pdf: 2549346 bytes, checksum: ef1926e6a6c799c77ce5ae93edd18467 (MD5) Previous issue date: 1969
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Bioorthogonal Functionalization of Elastin-like Polypeptides
<p>Recombinant technology has given us the powerful ability to imagine and create novel biological entities, from potent therapeutics to functionally active materials. By harnessing nature’s building blocks and reconfiguring these components, recombinant engineering unlocks the potential to tailor …
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Study on polypeptides of cyanobacterial photosystem 2
… this work was to characterize cyanobacterial PS2 polypeptides with particular respect to calcium binding. A number of cyanobacteria were studied by trypsin digestion of their thylakoid membranes which showed that using the same method of preparation some cyanobacteria produce everted thylakoid …
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Programmable Assembly of Elastin-like Polypeptides Within Droplet Microenvironments
… of programming the assembly of elastin-like polypeptides, an archetypal class of disordered proteins, into model organelles within droplet microenvironments. We synthesized a library of recombinant elastin-like polypeptides, and studied their phase separation and assembly into various …
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Development of polynorbornenes and polypeptides as versatile functional biomaterials
Polymer chemistry is an essential connection between organic chemistry, chemical biology and materials science. This living world has presented us many examples of the usages of polymers, such as delivery vehicle, recognition unit, support materials, information storage,5 and so on. Scientists have …
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Development and study of synthetic polypeptides for biomaterial applications
Creating new scaffolds for cells is critical to the development of new tissue engineering techniques. In this work, the synthesis of new polypeptide systems is discussed. These systems are intended for the formation of hydrogels which can then be used as cell substrates. Attempts at using the …
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Synthesis and testing of novel polypeptides for biological applications
… behavior of these macromolecules. Synthetic polypeptides have received attention because of their unique structural properties and biocompatibility. Like their naturally occurring analogs, these molecules have a poly(amino acid) backbone and posses the ability to fold into secondary …
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The Membrane Polypeptides of the Vacuolar System: Composition and Recycling
… the rapid, synchronous centrifugal flow of PL polypeptides to the cell surface. Evidence was also obtained for the continuous influx of representative samples of the PM into the PL compartment by way of pinocytic vesicles. This was based on the constant flow of fluid phase markers into …
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The α-helical conformation of polypeptides: design, regulation, and applications
Synthetic polypeptides have received increasing attention during the past two decades. Compared to other synthetic polymers, polypeptides share the same peptide backbones with naturally-occurring proteins, which allows them to form higher order structures spontaneously and enables their unique …
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Controlling Self -Assembly of Anisotropic, Rod-Like Polypeptides on Solid Surfaces
… we have focused on the assembly of rod-like polypeptides such as poly(gamma-benzyl-L-glutamate) (PBLG) on solid surfaces. These alpha-helical materials possess a rigid dipole moment parallel to their rod axis and their assembly at interfaces is relevant to applications in piezoelectric …
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Amino acid N-carboxyanhydrides and polypeptides: Controlled polymerization, properties and applications
… acid N-carboxyanhydrides (NCAs) and synthetic polypeptides based materials. Polypeptides are a class of emerging biomaterials receiving increasing interests for various applications including drug delivery, gene therapy, antimicrobial and tissue engineering. The ring-opening polymerization …
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Synthesis, nanostructure, and mechanics of thermoresponsively tough biomaterials from artificial polypeptides
… (PNIPAM) and elastin-like polypeptides (ELPs) was leveraged to assemble nanostructured hydrogels from dual-associative block copolymers. Hybrid protein-polymers or protein fusions were formed by fusing PNIPAM or ELPs to the termini of a soluble artificial polypeptide …
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Characterization of the alpha- and beta- tubulin polypeptides in Saccharomyces cerevisiae
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1995.
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FEXOFENADINE AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs): TRANSPORT AND DRUG-DRUG INTERACTIONS
Transporters play a major role in the absorption and disposition of fexofenadine, suggesting this drug could be used as a probe of transporter activity. When fexofenadine was administered in combination with four drugs (buspirone, caffeine, dextromethorphan and losartan) used to probe cytochrome …
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Cationic, α-helical polypeptides for cell penetration and non-viral gene delivery
… the chemical modification method to modify the polypeptides with the hydrophobic domain. A library of copolypeptides with different side chains modified by aromatic groups and aliphatic groups are synthesized and screened for cell penetration and gene delivery. This chemical modification …
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I. Collagen-like polypeptides. II. Helix-turn-helix peptides and turn mimetics
Collagen is one of the most important and abundant proteins in mammals. It consists of three left-handed PPII helixes coiled along a common axis to form a very compact right-handed super helix. The primary structure is shown to be (Gly-Xaa-Yaa)n repeats with high content of prolyl residues at both …
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