Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"polymer-peptide-conjugates"”.
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Design and synthesis of mechanoresponsive materials and multivalent polymer-peptide conjugates
Functional polymers have been studied extensively due to their versatility and ability to yield diverse materials with desirable properties. Polymers that are functionalized intrinsically are made using several strategies including specially designed monomers and post polymerization …
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Macromolecular design for modulation of amyloid fibrillar assembly
… describes a new class of rationally designed polymeric modulators which specifically target amyloid β oligomers and control amyloid aggregation. Chapter 2-3 focus on the design of series of polymer-peptide conjugates which redirect Aβ fibrillar assembly by stabilizing Aβ oligomers into …
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Polymerizable Peptide Monomers for the Targeted and Intracellular Delivery of Cancer Therapeutics
For the treatment of cancer, peptides hold great potential as both targeting and therapeutic agents. One particularly promising anti-cancer strategy is peptides derived from the third Bcl-2 homology domain (BH3), which antagonize pro-survival Bcl-2 proteins and induce apoptosis. Unfortunately, …
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Induktion und Kontrolle hierarchischer Ordnung durch selbstorganisierte, funktionale Polymer-Peptid-Nanostrukturen
Im Rahmen der Arbeit werden hierarchisch strukturierte Silikakompositfasern präsentiert, deren Bildung ähnlich zu natürlichen Silifizierungsreaktionen verläuft. Als Analoga zu Proteinfilamenten in Silika Morphogeneseorganismen werden selbstorganisierte, funktionale Polyethylenoxid-Peptid-Nanobänder …